Acetic acid, (N-acetyl-N-(3-fluorenyl)amino) ester

CAS 38105-27-0 MFCD01743523

化学结构图

38105-27-0
SMILES: CC(=O)ON(C1=CC2=C(CC3C=CC=CC2=3)C=C1)C(C)=O

化学属性

Mol. FormulaC17H15NO3
Mol. Weight281.33

别名和识别编码

Chemical NameAcetic acid, (N-acetyl-N-(3-fluorenyl)amino) ester
Wiswesser Line NotationL B656 HHJ DNV1&OV1
Synonym Acetic acid, ester with N-(fluoren-3-yl)acetohydroxamic acid N-Acetoxyfluorenylacetamide N-Acetoxy-3-fluorenylacetamide N-(Fluoren-3-yl)acetohydroxamic acetate
Beilstein Registry Number2759193
CAS Number38105-27-0
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安全信息

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 210 mg/kg/8W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   35,447,1975

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Implant
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 28 mg/kg
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   37,111,1977

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 350 mg/kg/4W-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Skin and Appendages - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   35,447,1975

RTECSAF1650000

系列性分类


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