Benzamide,3-bromo-2,6-dimethoxy-N-(1-ethyl-2-pyrrolidinylmethyl)-, hydrochloride, (S)-(-)-

CAS 73220-03-8 MFCD01743944

化学结构图

73220-03-8
SMILES: Cl.CCN1CCC[C@H]1CNC(=O)C1C(OC)=C(Br)C=CC=1OC

化学属性

Mol. FormulaC16H23BrN2O3
Mol. Weight371.32

别名和识别编码

Chemical NameBenzamide,3-bromo-2,6-dimethoxy-N-(1-ethyl-2-pyrrolidinylmethyl)-, hydrochloride, (S)-(-)-
CAS Number73220-03-8
Synonym (-)-Remoxipride Hydrochloride FLA 731 A 33547 A 33547 Hydrochloride (S)-(-)-2-((3-Bromo-2,6-dimethoxybenzamido)methyl)-1-ethylpyrrolidine (-)-FLA 731 (- 3-Bromo-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2,6-dimethoxybenzamide Hydrochloride Remoxipride Hydrochloride
Wiswesser Line NotationT5NTJ A2 B1MVR CE BO1 FO1 &GH
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分类

  • Aromatics
  • Heterocycles
  • Chiral Reagents
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • Specific dopamine D2-receptor antagonist. Antipsychotic.

相关文献及参考

  • Ogren, S.O., et al.: Eur. J. Pharmacol., 102, 459 (1984),

安全信息

RTECSCV2369000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 324 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - rigidity (including catalepsy)
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 25,1280,1982

系列性分类

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