TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 60 mg/kg
SEX/DURATION            : female 12 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Maternal Effects - menstrual cycle changes or disorders
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   ATTHEH Acta Toxicologica et Therapeutica.  (Casa Editrice Maccari, Casella
   Postale 120, I-43100 Parma, Italy)  V.1-    1980-  Volume(issue)/page/year:
   15,181,1994

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 3 gm/kg
SEX/DURATION            : female 12 day(s) pre-mating
                          female 1-18 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   ATTHEH Acta Toxicologica et Therapeutica.  (Casa Editrice Maccari, Casella
   Postale 120, I-43100 Parma, Italy)  V.1-    1980-  Volume(issue)/page/year:
   15,181,1994

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 3 gm/kg
SEX/DURATION            : female 12 day(s) pre-mating
                          female 1-18 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Maternal Effects - menstrual cycle changes or disorders
   Reproductive - Maternal Effects - other effects
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   ATTHEH Acta Toxicologica et Therapeutica.  (Casa Editrice Maccari, Casella
   Postale 120, I-43100 Parma, Italy)  V.1-    1980-  Volume(issue)/page/year:
   15,181,1994