1H-Imidazole,4,5-dihydro-2-(2,2-diphenylcyclopropyl)-, succinate(2:1)

CAS 57625-97-5 MFCD01960862

化学结构图

57625-97-5
SMILES: OC(=O)CCC(O)=O.C1C(C2NCCN=2)C1(C1C=CC=CC=1)C1C=CC=CC=1.C1C(C2NCCN=2)C1(C1C=CC=CC=1)C1C=CC=CC=1

化学属性

Mol. FormulaC36H36N4.C4H6O4
Mol. Weight642.86

别名和识别编码

Chemical Name1H-Imidazole,4,5-dihydro-2-(2,2-diphenylcyclopropyl)-, succinate(2:1)
Synonym 2-(2,2-Diphenylcyclopropyl)-4,5-dihydro-1H-imidazole succinate (2:1)
CAS Number57625-97-5
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安全信息

RTECSNI4804900 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 300 mg/kg/22W-I
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - ptosis
   Behavioral - muscle weakness
REFERENCE :
   IEDIEP Internal Medicine.  (The Japanese Society of Internal Medicine, 34-3,
   3-chome, Hongo, Bunkyo-ku, Tokyo 113, Japan)  V.31-    1992-
   Volume(issue)/page/year: 35,512,1996

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 41500 ug/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - ptosis
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   KSRNAM Kiso to Rinsho.  Clinical Report.  (Yubunsha Co., Ltd., 1-5, Kanda
   Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan)  V.1-    1960-
   Volume(issue)/page/year: 22,4485,1988

系列性分类

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