(+)-Nicotine (+)-尼古丁

CAS 25162-00-9 MFCD00210122

化学结构图

25162-00-9
SMILES: CN1CCC[C@@H]1C1C=NC=CC=1 |&1:5|

化学属性

Mol. Weight162.23
Mol. FormulaC10H14N2

别名和识别编码

CAS Number25162-00-9
Chemical Name(+)-Nicotine
Synonym (+)-Nicotine (R)-3-(1-Methyl-2-pyrrolidinyl) (R)-3-(1-Methyl-2-pyrrolidinyl)pyridine D-Nicotine 2'?H-Nicotine d-Nicotine Pseudonicotine 3-[(2R)-1-Methyl-2-pyrrolidinyl]pyridine Pyridine, 3-(1-methyl-2-pyrrolidinyl)-, (R)-
Chemical Name Translation(+)-尼古丁
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分类

  • Chiral Reagents
  • Heterocycles
  • Mutagenesis Research Chemicals
  • Nicotine Derivatives,

产品应用

  • (R)-(+)-Nicotine is the R-enantiomer of Nicotine (N412420) extracted from tobacco leaves. The results showed that native nicotine contained 98% S-Nicotine and 2% R-Nicotine. ?

相关文献及参考

  • Barlow, R., et al.: Br. J. Pharmacol ., 25, 206 (1965),
  • Armstrong, D., et al.: Chirality, 11, 82 (1999),

安全信息

RTECSQS5260000 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Cardiac - pulse rate
   Vascular - BP elevation not characterized in autonomic section
REFERENCE :
   85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme
   Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948
    Volume(issue)/page/year: -,584,1948

系列性分类

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