Epothilone D 埃坡霉素D

CAS 189453-10-9 MFCD02102104

化学结构图

189453-10-9
SMILES: C/C(=C\C1=CSC(C)=N1)/[C@@H]1CC=CCCC[C@H](C)[C@H](O)[C@@H](C)C(=O)C(C)(C)[C@@H](O)CC(=O)O1

化学属性

Mol. FormulaC27H41NO5S
Mol. Weight491.68

别名和识别编码

Chemical NameEpothilone D
CAS Number189453-10-9
Synonym ########
Chemical Name Translation埃坡霉素D
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • Chiral Reagents
  • Inhibitors
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Sulfur & Selenium Compounds

产品应用

  • ########

相关文献及参考

  • [2]. Brunden KR, et al. Epothilone D improves microtubule density, axonal integrity, and cognition in a transgenic mouse model of tauopathy. J Neurosci. 2010 Oct 13;30(41):13861-6.
  • Bollag, D.M., et al.: Cancer. Res., 55, 2325 (1995),
  • Hardt, I.H., et al.: J. Nat. Prod., 64, 847 (2001),
  • [1]. Konner J, et al. Phase I clinical, pharmacokinetic, and pharmacodynamic study of KOS-862 (Epothilone D) in patients with advanced solid tumors and lymphoma. Invest New Drugs. 2012 Dec;30(6):2294-302.
  • [1]. Konner J, et al. Phase I clinical, pharmacokinetic, and pharmacodynamic study of KOS-862 (Epothilone D) in patients with advanced solid tumors and lymphoma. Invest New Drugs. 2012 Dec;30(6):2294-302.
  • [2]. Brunden KR, et al. Epothilone D improves microtubule density, axonal integrity, and cognition in a transgenic mouse model of tauopathy. J Neurosci. 2010 Oct 13;30(41):13861-6.

系列性分类

  1. Medical Research Areas
  2. Cytosketetal Signaling
  3. Microtubule/Tubulin  (微管/微管蛋白)

相关产品推荐