Pramipexole Dihydrochloride Monohydrate 普拉克索二盐酸盐一水合物

CAS 191217-81-9 MFCD02183927

化学结构图

191217-81-9
SMILES: O.Cl.Cl.CCCN[C@@H]1CC2SC(N)=NC=2CC1

化学属性

Mol. FormulaC10H17N3S·2HCl·H2O
Mol. Weight302

别名和识别编码

Chemical NamePramipexole Dihydrochloride Monohydrate
Chemical Name Translation普拉克索二盐酸盐一水合物
MDL NumberMFCD02183927
Reaxys-RN14116907
Merck Number7705
PubChem Substance ID253659970
CAS Number191217-81-9
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相关文献及参考

  • [2]. Takashi Okura, et al. Blood-brain barrier transport of pramipexole, a dopamine D2 agonist. Life Sci. 2007 Apr 3;80(17):1564-71.
  • [3]. Ginetta Collo, et al. Ropinirole and Pramipexole Promote Structural Plasticity in Human iPSC-Derived Dopaminergic Neurons via BDNF and mTOR Signaling. Neural Plast. 2018; 2018: 4196961.
  • [4]. P M Carvey, et al. Attenuation of levodopa-induced toxicity in mesencephalic cultures by pramipexole. J Neural Transm (Vienna). 1997;104(2-3):209-28.
  • [5]. Syed Suhail Andrabi, et al. Pramipexole prevents ischemic cell death via mitochondrial pathways in ischemic stroke. Dis Model Mech. 2019 Aug 1; 12(8): dmm033860.
  • [1]. Kvernmo, T., et al. A review of the receptor-binding and pharmacokinetic properties of dopamine agonists. Clin Ther, 2006. 28(8): p. 1065-78.
  • [1]. Kvernmo, T., et al. A review of the receptor-binding and pharmacokinetic properties of dopamine agonists. Clin Ther, 2006. 28(8): p. 1065-78.
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安全信息

GHS Symbol
UN Number 3077
Hazard Codes 9
Signal word Warning
WGK Germany3
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P301+P312
  • P301+P312+P330
  • P304+P340+P312
  • P330 Rinse mouth. 漱口
  • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Packing GroupIII
RTECSDL3375000
Hazard statements
  • H302 Harmful if swallowed 吞食有害

系列性分类


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