Meperidide

CAS 2266-22-0 MFCD02266220

化学结构图

2266-22-0
SMILES: Cc1cccc(C2(C(=O)N3CCCC3)CCN(CCCC(=O)c3ccc(F)cc3)CC2)c1

化学属性

Mol. FormulaC27H33FN2O2
Mol. Weight436.62

别名和识别编码

Synonym 1-((1-(4-(4-Fluorophenyl)-4-oxobutyl)-4-(3-methylphenyl)-4-piperidinyl)carbonyl)pyrrolidine R 2963 Methylperidide Pyrrolidine, 1-(1-(3-(p-fluorobenzoyl)propyl)-4-m-tolylisonipecotoyl)- Meperidide
Chemical NameMeperidide
CAS Number2266-22-0
Beilstein Registry Number0502326
InChIKeyQFLXBYDLGCRGPT-UHFFFAOYSA-N
PubChem Substance ID3034126
InChIInChI=1S/C27H33FN2O2/c1-21-6-4-7-23(20-21)27(26(32)30-16-2-3-17-30)13-18-29(19-14-27)15-5-8-25(31)22-9-11-24(28)12-10-22/h4,6-7,9-12,20H,2-3,5,8,13-19H2,1H3
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安全信息

RTECSUY1257300 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Primate - monkey
DOSE/DURATION           : >1250 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 11,932,1961

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : >20 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 11,932,1961

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 9300 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,191,1972

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 275 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issu

系列性分类

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