Dichlorisone

CAS 7008-26-6 MFCD00232919

化学结构图

7008-26-6
SMILES: C[C@]12CC(Cl)[C@@]3(Cl)[C@@H](CCC4=CC(=O)C=C[C@@]43C)[C@@H]1CC[C@]2(O)C(=O)CO

化学属性

Mol. FormulaC₂₁H₂₆Cl₂O₄
Mol. Weight413.33
Melting Point>215°C (dec.)
Boiling Point

别名和识别编码

Chemical NameDichlorisone
CAS Number7008-26-6
Synonym (11?)-9,11-Dichloro-17,21-dihydroxypregna-1,4-diene-3,20-dione 9,11?-Dichloro-17,21-dihydroxypregna-1,4-diene-3,20-dione 9?,11?-Dichloro-17?,21-dihydroxypregna-1,4-diene-3,20-dione Dichlorisone
Chemical Name Translation
PubChem Substance ID20054892
InChIInChI=1S/C21H26Cl2O4/c1-18-7-5-13(25)9-12(18)3-4-15-14-6-8-20(27,17(26)11-24)19(14,2)10-16(22)21(15,18)23/h5,7,9,14-16,24,27H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,18-,19-,20-,21-/m0/s1
MDL Number
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分类

  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Steroids

产品应用

  • Dichlorisone is a 9?,11?-dichloro corticoid. Dichlorisone has anti-antiinflammatory potency. Dichlorisone could be modifed to be used as glucocorticoid receptor agonists as well as a P-glycoprotein in

相关文献及参考

  • Collins, E.J. et al.: Proc. Int. Congr. Horm. Steroids, 2, 530 (1967); Gruol, D.J. et al.: Cancer Res., 57, 720 (1997);

安全信息

Storage condition -20

系列性分类

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