N-(Deoxyguanosin-8-yl)-2-amino-1-methyl-6-phenylimidazo[4,5-?]pyridine
CAS 142784-25-6 MFCD02683305
化学结构图
SMILES: CN1C(NC2=NC3=C(NC(=N)NC3=O)N2[C@H]2C[C@H](O)[C@@H](CO)O2)=NC2N=CC(=CC1=2)C1C=CC=CC=1
化学属性
| Mol. Formula | C23H23N9O4 |
|---|---|
| Mol. Weight | 489 |
别名和识别编码
| Chemical Name | N-(Deoxyguanosin-8-yl)-2-amino-1-methyl-6-phenylimidazo[4,5-?]pyridine |
|---|---|
| CAS Number | 142784-25-6 |
| Synonym | 2'-Deoxy-8-[(1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-yl)amino]guanosine dG-C8-PhIP |
| Chemical Name Translation | |
| MDL Number | MFCD02683305 |
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分类
- Mutagenesis Research Chemicals
- Nucleotides
- Bases & Related Reagents
产品应用
- The DNA adduct formed from N-Hydroxy-PHIP. Mutagenic nucleotide incorporation and hindered translocation by a food carcinogen C8-dG adduct in Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4).
相关文献及参考
- Frandsen, H., et al.: Carcinogenesis, 13, 4, 629 (1992),
- Lin, D., et al.: Chem. Res. Toxicol., 5, 691 (1993),
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