(R)-1-Benzylpiperidin-3-Ol (R)-(-)-1-苄基-3-羟基哌啶

CAS 91599-81-4 MFCD00274307

化学结构图

91599-81-4
SMILES: O[C@H]1CN(CC2C=CC=CC=2)CCC1

化学属性

Mol. FormulaC12H17NO
Mol. Weight191.27
Refractive index1.5460 to 1.5500
Boiling Point102°C/0.4mmHg(lit.)
Density1.07
TSCANo

别名和识别编码

Chemical Name(R)-1-Benzylpiperidin-3-Ol
CAS Number91599-81-4
Synonym (R)-(-)-1-苄基-3-羟基哌啶 (R)-(-)-1-Benzyl-3-hydroxypiperidine (R)-1-(Phenylmethyl)-3-piperidinol (R)-1-Benzyl-3-piperidinol (R)-1-苄基-3-哌啶醇
PubChem Substance ID253660962
MDL NumberMFCD00274307
Chemical Name Translation(R)-(-)-1-苄基-3-羟基哌啶
Reaxys-RN6998795
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分类

  • Pharmaceuticals
  • Heterocycles
  • Aromatics
  • Intermediates & Fine Chemicals
  • {SNA} Asymmetric Synthesis, Chemical Synthesis, Chiral Building Blocks, Heterocyclic Building Blocks, Piperidines

产品应用

  • (R)-1-Benzyl-3-piperidinol is a benzylpiperidine derivative with hypotensive affects. (R)-1-Benzyl-3-piperidinol is used in the preparation of in vivo probes for measuring endogenous acetylcholine lev

相关文献及参考

  • Muto, K. et al.: Arzneim.-Forsch., 38, 1662 (1988); Skaddan, M.B. et al.: J. Med. Chem., 43, 4552 (2000);

安全信息

GHS Symbol
WGK Germany3
Hazard statements
  • H301 Toxic if swallowed 吞食有毒
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P310
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338
  • P305+P351+P338+P337+P313
Signal word
Hazard Codes T
Risk Statements
  • R25 Toxic if swallowed 吞咽有毒
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S37 Wear suitable gloves 戴适当手套；
UN Number
Packing GroupIII

系列性分类

  1. Chemical Synthesis 化学合成
  2. Asymmetric Synthesis 不对称合成
  3. Chiral Building Blocks 手性分子砌块
  4. Heterocyclic Building Blocks - Chiral Building Blocks
  5. Piperidines - Heterocyclic Building Blocks
  1. Chemical Synthesis 化学合成
  2. Asymmetric Synthesis 不对称合成
  3. Chiral Building Blocks 手性分子砌块
  4. Heterocyclic Building Blocks - Chiral Building Blocks
  5. Piperidines - Heterocyclic Building Blocks

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