• 原料直供
• 试剂商城
• 直接询价

分类

• {SNA} Approved Therapeutics/Drug Candidates, B, Bioactive Small Molecule Alphabetical Index, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, GlaxoSmithKline, P to Q, Phosphodiesterase 7, 生化试剂, 生物活性小分子, 细胞生物学, 酶、抑制剂和底物
• Inhibitors
• {SNA} Approved Therapeutics/Drug Candidates, B, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, GlaxoSmithKline, P to Q, Phosphodiesterase 7

产品应用

• A PDE7 inhibitor that has acceptable selectivity for in vivo studies.

相关文献及参考

• [2]. Smith SJ, et al. Discovery of BRL 50481 [3-(N,N-dimethylsulfonamido)-4-methyl-nitrobenzene], a selective inhibitor of phosphodiesterase 7: in vitro studies in human monocytes, lung macrophages, and CD8+ T-lymphocytes. Mol Pharmacol. 2004 Dec;66(6):1679-89.
• Smith, S.J., et al., Discovery of BRL 50481, a selective inhibitor of phosphodiesterase 7: In vitro studies in human monocytes, lung macrophages and CD8 + T-lymphocytes. Mol. Pharmacol. 66 , 1679-1689 , (2004)
• Smith, S.J., et al.: Mol. Pharmacol., 66, 1679 (2004)
• [1]. Safavi M, et al. New methods for the discovery and synthesis of PDE7 inhibitors as new drugs for neurologicaland inflammatory disorders. Expert Opin Drug Discov. 2013 Jun;8(6):733-51.
• [1]. Safavi M, et al. New methods for the discovery and synthesis of PDE7 inhibitors as new drugs for neurologicaland inflammatory disorders. Expert Opin Drug Discov. 2013 Jun;8(6):733-51.
• [2]. Smith SJ, et al. Discovery of BRL 50481

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