3-[3-[2,5-DIHYDRO-4-(1-METHYL-1H-INDOL-3-YL)-2,5-DIOXO-1H-PYRROL-3-YL]-1H-INDOL-1-YL]PROPYL CARBAMIMIDOTHIOIC ACID ESTER MESYLATE

CAS 125314-64-9 MFCD03788207

化学结构图

125314-64-9
SMILES: CN1C=C(C2=C(C3=CN(CCCSC(N)=N)C4C=CC=CC=43)C(=O)NC2=O)C2C=CC=CC1=2.CS(O)(=O)=O

化学属性

Mol. FormulaC25H23N5O2S · CH3SO3H
Mol. Weight553.65

别名和识别编码

Chemical NameRo 31-8220 methanesulfonate salt
Synonym 2-{1-[3-(Amidinothio)propyl]-1H-indol-3-yl}-3-(1-methylindol-3-yl)maleimide methanesulfonate salt Bisindoylmaleimidine IX
MDL NumberMFCD03788207
PubChem Substance ID329824000
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SA} Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates,
  • {SNA} Bioactive Small Molecule Alphabetical Index, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Kinase/Phosphatase Biology, L to O, MAPKAP kinase-1beta and p70 S6 kinase, Protein Kinase Inhibitors, Protein kinase C, G-protein coupled receptor kinase, MAPK-activated protein kinase (PKC, GRK, MAPKAP Kinase), R, Serine/Threonine Kinase Biology, Serine/Threonine Kinase Inhibitors, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 酶、抑制剂和底物

相关文献及参考

  • Moore, J.B., et al., Inhibition of PTH desensitization by inhibition of the G protein-coupled receptor kinase-5 enzyme with Ro 32-0432. FASEB J. 12 , A741, (1998)
  • Beltman, J., et al., The selective protein kinase C inhibitor Ro-31-8220 inhibits mitogen-activated protein kinase phosphatase-1 (MKP-1) expression induces c-Jun expression and activates J N-terminal kinase. J. Biol. Chem. 271 , 27018, (1996) 摘要
  • Alessi, D.R., The protein kinase C inhibitors Ro 318220 and GF 109203X are equally potent inhibitors of MAPKAP kinase –1β (Rsk-2) and p70 S6 kinase. FEBS Lett. 402 , 121-123, (1997) 摘要

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Inhibitors - Enzymes, Inhibitors, and Substrates
  5. Enzyme Inhibitors by Enzyme - Enzyme Inhibitors
  6. L to O - Enzyme Inhibitors by Enzyme
  7. MAPKAP kinase-1beta and p70 S6 kinase - L to O

相关产品推荐