Enprofylline 恩丙茶碱

CAS 41078-02-8 MFCD00043205

化学结构图

41078-02-8
SMILES: CCCN1C(=O)NC(=O)C2NC=NC1=2

化学属性

Mol. FormulaC8H10N4O2
Mol. Weight194.22

别名和识别编码

Chemical NameEnprofylline
Synonym 3,7-Dihydro-3-propyl-1H-purine-2,6-dione Nilyph Enprofylline D-4028 3-Propylxanthine Oxeze
PubChem Substance ID24277687
EC Number255-201-8
Beilstein Registry Number1116213
MDL NumberMFCD00043205
CAS Number41078-02-8
Chemical Name Translation恩丙茶碱
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分类

  • {SA} Adenosines/P2 Nucleotide Receptors (Purinergics), Antagonists, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Neuroscience, Neurotransmission, Neurotransmitters, P

安全信息

GHS Symbol
WGK Germany3
Hazard statements
  • H332 Harmful if inhaled 吸入有害
  • H302 Harmful if swallowed 吞食有害
  • H312 Harmful in contact with skin 皮肤接触有害
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
RTECSUO8439700
Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
Signal word Warning
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 254 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PLRCAT Pharmacological Research Communications.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802)  V.1-    1969-  Volume(issue)/page/year:
   22(Suppl 2),125,1990

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 481 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PLRCAT Pharmacological Research Communications.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802)  V.1-    1969-  Volume(issue)/page/year:
   22(Suppl 2),125,1990

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 157 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
REFERENCE :
   APTOA6 Acta Pharmacologica et Toxicologica.  (Copenhagen, Denmark)  V.1-59,
   1945-86.  For publisher information, see PHTOEH  Volume(issue)/page/year:
   49,313,1981

系列性分类


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