2,2',5,5'-Tetrachlorobenzidine 2,2,5,5-四氯二苯胺

CAS 15721-02-5 MFCD00043918

化学结构图

15721-02-5
SMILES: NC1C=C(Cl)C(=CC=1Cl)C1C=C(Cl)C(N)=CC=1Cl

化学属性

Mol. FormulaC12H8Cl4N2
Mol. Weight322.01
Melting Point137.0 to 141.0 deg-C

别名和识别编码

Chemical Name2,2',5,5'-Tetrachlorobenzidine
MDL NumberMFCD00043918
PubChem Substance ID87576751
EC Number239-815-3
CAS Number15721-02-5
Synonym 2,2',5,5'-Tetrachloro-4,4'-diaminodiphenyl 3,3',6,6'-Tetrachlorobenzidine 2,2',5,5'-Tetrachlorobenzidine 2,2',5,5'-Tetrachloro-(1,1'-biphenyl)-4,4'-diamine Tetrachlorobenzidine 2,2',5,5'-Tetrachloro-[1,1'-Biphenyl]-4,4'-diamine (1,1'-Biphenyl)-4,4'-diamine, 2,2',5,5'-tetrachloro-
Reaxys-RN3364286
Chemical Name Translation2,2,5,5-四氯二苯胺
Wiswesser Line NotationZR BG EG DR DZ CG FG
Beilstein Registry Number3364286
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安全信息

WGK Germany3
RTECSDD1751000
Signal word
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P332+P313
  • P305+P351+P338+P337+P313
  • P302+P350
  • P337+P313
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338
GHS Symbol 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 54 mg/kg/43W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Kidney, Ureter, Bladder - tumors
   Blood - lymphoma, including Hodgkin's disease
REFERENCE :
   JMEJAS Jikeikai Medical Journal.  (Jikei Univ. School of Medicine, 3-25-8
   Nishi-shinbashi, Minato-ku, Tokyo 105, Japan)  V.1-    1954-
   Volume(issue)/page/year: 25,123,1978

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 36 mg/kg/43W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Kidney, Ureter, Bladder - tumors
   Blood - lymphoma, including Hodgkin's disease
REFERENCE :
   JMEJAS Jikeikai Medical Journal.  (Jikei Univ. School of Medicine, 3-25-8
   Nishi-shinbashi, Minato-ku, Tokyo 105, Japan)  V.1-    1954-
   Volume(issue)/page/year: 25,123,1978

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 gm/kg/43W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Skin and Appendages - tumors
REFERENCE :
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 27,141,1982

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 900 gm/kg/43W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Kidney, Ureter, Bladder - tumors
REFERENCE :
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk

系列性分类

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