东莨菪碱, 来源于颠茄 东莨菪碱, 来源于颠茄

CAS 51-34-3 MFCD05662373

化学结构图

51-34-3
SMILES: CN1C2CC(OC(=O)C(CO)c3ccccc3)CC1C1OC12

化学属性

Mol. FormulaC17H21NO4
Mol. Weight303.39
Density1.31
Boiling Point460.3
Melting Point59

别名和识别编码

Chemical NameScopolamine
MDL NumberMFCD05662373
Synonym Hyosol Atrochin Epoxytropine tropate Isopto hyoscine Hyosceine Atroquin Hyoscine (-)-Hyoscine Oscine 3-Oxa-9-azatricyclo(3.3.1.O(sup 2,4))nonan-7-ol, 9-methyl-, tropate 6-beta,7-beta-Epoxy-3-alpha-tropanyl S-(-)-tropate (-)-SCOPOLAMINE
CAS Number51-34-3
Chemical Name Translation东莨菪碱, 来源于颠茄
Wiswesser Line NotationT C356 A AN DOTJ A1 HOVYR&1Q
LabNetwork Molecule IDLN01808504
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

安全信息

GHS Symbol
Safety Statements
  • S25 Avoid contact with eyes 避免眼睛接触;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
Risk Statements
  • R26/27/28 Very toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有剧毒
RTECSVR3675000
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Human
DOSE/DURATION           : 4 ug/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
   Behavioral - hallucinations, distorted perceptions
REFERENCE :
   85IVAW "Possible Long-Term Health Effects of Short-Term Exposure to Chemical
   Agents," National Research Council, 3 vols., Washington, DC, National
   Academy Press, 1982-85  Volume(issue)/page/year: 1,L1,1982

{h

TYPE OF TEST            : LD50 - Lethal dose

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2650 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FMCHA2 Farm Chemicals Handbook.  (Meister Pub., 37841 Euclid Ave.,
   Willoughy, OH 44094)  Volume(issue)/page/year: -,C272,1991

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 24 ug/kg
TOXIC EFFECTS :
   Behavioral - hallucinations, distorted perceptions
REFERENCE :
   FEPRA7 Federation Proceedings, Federation of American Societies for
   Experimental Biology. (Bethesda, MD)  V.1-46, 1942-87.
   Volume(issue)/page/year: 32,250,1973

TYPE OF TEST            : TDLo - Lowest published toxic dos

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 75 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
   Ger. Dem. Rep.)  Volume(issue)/page/year: 4,1289,1935

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Human Leukocyte
DOSE/DURATION           : 1 pph/22H
REFERENCE :
   22XWAN "Chemical Mutagenesis in Mammals and Man," Vogel, F., and G.
   Roehrborn, eds., Berlin, Fed. Rep. Ger., Springer, 1970
   Volume(issue)/page/year: -,367,1970

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 1 mg/L
REFERENCE :
   CMJODS Chinese Medical Journal (Beijing, English Edition).  (China
   International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 
     1975-    Adopted vol. no. 92 in 1979.  Volume(issue)/page/year:
   101,339,1988

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 1 mg/L
REFERENCE :
   CMJODS Chinese Medical Journal (Beijing, English Edition).  (China
   International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 
     1975-    Adopted vol. no. 92 in 1979.  Volume(issue)/page/year:
   101,339,1988

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 50600 ug/kg
SEX/DURATION            : female 6-16 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   CMJODS Chinese Medical Journal (Beijing, English Edition).  (China
   International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 
     1975-    Adopted vol. no. 92 in 1979.  Volume(issue)/page/year:
   101,339,1988

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 1 mg/kg
SEX/DURATION            : female 13 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - biochemical and metabolic
   Reproductive - Effects on Newborn - behavioral
REFERENCE :
   FEPRA7 Federation Proceedings, Federation of American Societies for
   Experimental Biology. (Bethesda, MD)  V.1-46, 1942-87.
   Volume(issue)/page/year: 31,596,1972

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 649 mg/kg
SEX/DURATION            : female 6-16 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   CMJODS Chinese Medical Journal (Beijing, English Edition).  (China
   International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 
     1975-    Adopted vol. no. 92 in 1979.  Volume(issue)/page/year:
   101,339,1988

其他信息

  • MOL 文件:138-12-5.mol

系列性分类


相关产品推荐