5-Amino-2,4-dichloropyrimidine 5-氨基-2,4-二氯嘧啶

CAS 5177-27-5 MFCD05662684

化学结构图

5177-27-5
SMILES: Nc1cnc(Cl)nc1Cl

化学属性

Mol. FormulaC4H3Cl2N3
Mol. Weight163.99
Melting Point118-123°C
TSCANo
Stability对热、光、湿度敏感
Boiling Point290.7±20.0 °C at 760 mmHg

别名和识别编码

Chemical Name5-Amino-2,4-dichloropyrimidine
CAS Number5177-27-5
Alfabeta NameAMINODICHLOROPYRIMIDINE 524---,
MDL NumberMFCD05662684
Synonym 5-Amino-2,4-dichloropyrimidine {LY} 5-Amino-2,4-dichloropyrimidine {} {LY} 5-Amino-2,4-dichloropyrimidine {} {} {LY} 5-Amino-2,4-dichloropyrimidine {} {} {} {LY} 5-Amino-2,4-dichloropyrimidine {} {} {} {} {LY} 5-Amino-2,4-dichloropyrimidine {} {} {} {} {} {LY} 5-Amino-2,4-dichloropyrimidine {} {} {} {} {} {} {LY} 5-Amino-2,4-dichloropyrimidine {} {} {} {} {} {} {} {LY} 5-Amino-2,4-dichloropyrimidine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 5-Amino-2,4-dichloropyrimidine {} {} {} {} {} {} {} {} {} {LY} 5-Amino-2,4-dichloropyrimidine {} {} {} {} {} {} {} {} {} {} {LY} 5-Amino-2,4-dichloropyrimidine {} {} {} {} {} {} {} {} {} {} {} {LY} 5-Amino-2,4-dichloropyrimidine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 5-Amino-2,4-dichloropyrimidine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 5-Amino-2,4-dichloropyrimidine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 5-Amino-2,4-dichlorop
Chemical Name Translation5-氨基-2,4-二氯嘧啶
PubChem Substance ID257797
LabNetwork Molecule IDLN00173466
InChIInChI=1S/C4H3Cl2N3/c5-3-2(7)1-8-4(6)9-3/h1H,7H2
Canonical SMILESC1=C(C(=NC(=N1)Cl)Cl)N
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分类

  • {SNA} Building Blocks, C4 to C5, Chemical Synthesis, Heterocyclic Building Blocks, Pyrimidines
  • Heterocycles
  • Pharmaceuticals
  • Amines
  • Intermediates & Fine Chemicals
  • Aromatics

产品应用

  • A pyrimidinamine derivative which may act as a Plk1 inhibitor

相关文献及参考

  • O'Brien, D.E.

安全信息

Warnings IRRITANT
GHS Symbol
WGK Germany3
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛,皮肤或衣服。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P310
  • P302+P352
  • P304+P340
  • P305+P351+P338
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P330 Rinse mouth. 漱口
  • P332+P313
  • P333+P313
  • P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H301 Toxic if swallowed 吞食有毒
  • H315 Causes skin irritation 会刺激皮肤
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
  • H318 Causes serious eye damage 严重伤害眼睛
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Signal word Danger
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
Hazard Codes Xn
Risk Statements
  • R37/38 Irritating to respiratory system and skin 对呼吸系统和皮肤有刺激性
  • R22 Harmful if swallowed 吞咽有害
  • R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Storage condition -20°C, sealed storage, away from moisture and light {LY} -20°C, sealed storage, away from moisture and light {} {LY} -20°C, sealed storage, away from moisture and light {} {} {LY} -20°C, sealed storage, away from moisture and light {} {} {} {LY} -20°C, sealed storage, away from moisture and light {} {} {} {} {LY} -20°C, sealed storage, away from moisture and light {} {} {} {} {} {LY} -20°C, sealed storage, away from moisture and light {} {} {} {} {} {} {LY} -20°C, sealed storage, away from moisture and light {} {} {} {} {} {} {} {LY} -20°C, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {LY} -20°C, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {} {LY} -20°C, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {} {} {LY} -20°C, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C

其他信息

  • MOL 文件:5177-27-5.mol

系列性分类


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