5-Chloro-2-Fluorophenylboronic Acid 5-氯-2-氟苯硼酸

CAS 352535-83-2 MFCD05664225

化学结构图

352535-83-2
SMILES: OB(O)C1C=C(Cl)C=CC=1F

化学属性

Mol. FormulaC6H5BClFO2
Mol. Weight174
Melting Point122-127
TSCANo

别名和识别编码

Chemical Name5-Chloro-2-Fluorophenylboronic Acid
CAS Number352535-83-2
Alfabeta NameCHLOROFLUOROPHENYLBORONICACID 52---
MDL NumberMFCD05664225
PubChem Substance ID160871241
Synonym 5-氯-2-氟苯硼酸 5-Chloro-2-fluorophenylboronic acid
Chemical Name Translation5-氯-2-氟苯硼酸
Reaxys-RN9389054
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分类

  • Aryl Boronic Acids, Boronic Acids, Boronic Acids and Derivatives, Chemical Synthesis, Disubstituted Aryl Boronic Acids, Organometallic Reagents
  • {SNA} Aryl Boronic Acids, Boronic Acids, Boronic Acids and Derivatives, Chemical Synthesis, Disubstituted Aryl Boronic Acids, Organometallic Reagents

相关文献及参考

  • 1. E. Dubost, et al., , General method for the synthesis of substituted phenanthridin-6(5 H )-ones using a KOH-mediated anionic ring closure as the key step Tetrahedron 66 , 5008-5016, (2010)
  • 2. B. Budzik, et al., , 2' Biaryl amides as novel and subtype selective M1 agonists. Part I: Identification, synthesis, and initial SAR Bioorg. Med. Chem. Lett. 20 , 3540-3544, (2010)
  • 3. A. J. Roecker, et al., , Kinesin spindle protein (KSP) inhibitors. Part 8: Design and synthesis of 1,4-diaryl-4,5-dihydropyrazoles as potent inhibitors of the mitotic kinesin KSP Bioorg. Med. Chem. Lett. 17 , 5677-5682, (2007)
  • 4. M. Cameron, et al., , The Expedient Synthesis of 4,2'-Difluoro-5'-(7-trifluoromethylimidazo[1,2-a]pyrimidin-3-yl)biphenyl-2-carbonitrile, a GABA a2/3 Agonist Org. Process Res. Dev. 10 , 398-402, (2006)

安全信息

Warnings IRRITANT
WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Safety Statements
Risk Statements
Signal word
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
GHS Symbol
Precautionary statements
  • P501a
  • P405 Store locked up. 上锁保管。
  • P304+P340
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P305+P351+P338
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338+P337+P313

系列性分类


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