2-(4-(1-Oxoisoindolin-2-Yl)Phenyl)Butanoic Acid 2-(4-(1-氧代-2-异吲哚啉基)苯基)丁酸

CAS 63610-08-2 MFCD00572250

化学结构图

63610-08-2
SMILES: CCC(C(O)=O)C1C=CC(=CC=1)N1CC2C=CC=CC=2C1=O

化学属性

Mol. FormulaC18H17NO3
Mol. Weight295.36

别名和识别编码

Chemical Name2-(4-(1-Oxoisoindolin-2-Yl)Phenyl)Butanoic Acid
CAS Number63610-08-2
Synonym (?)-Indobufen 4-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-alpha-ethyl-benzeneacetic acid 1-Oxo-2-[p-[(?-ethyl)carboxymethyl]phenyl]isoindoline K 2930 K-3920 Indobufen Ibustrin 1-Oxo-2-(p-((alpha-ethyl)carboxymethyl)phenyl)isoindoline 2-[p-(1-Oxo-2-isoindolinyl)phenyl]butyric Acid 4-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-?-ethylbenzeneacetic Acid
Wiswesser Line NotationT56 BVN DHJ CR DY2&VQ
Chemical Name Translation2-(4-(1-氧代-2-异吲哚啉基)苯基)丁酸
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分类

  • Amines
  • Aromatics
  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • Indobufen is a platelet aggregation inhibitor. Indobufen is the anticoagulant drug and platelet aggregation inhibitor, which has anti-inflammatory analgesic effect. Indobufen is used as an antithrombo

相关文献及参考

  • Diener, H., et al.: J. Neurol. Sci., 143, 1 (1996),
  • Brainin, M., et al.: Eur. J. Neurol., 7, 5 (2005),
  • Culebras, A., et al.: Neurology, 62, 1073 (2004),
  • Lopez, A., et al.: Lancet, 367, 1747 (2006),

安全信息

RTECSET5955800
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 370 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   4,109,1979

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 333 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   4,109,1979

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 345 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   4,109,1979

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 373 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   4,109,1979

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION

{hazard_com}

系列性分类


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