Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-,lambda-lactone, (5Z,9-alpha,11-alpha, 13E,15S)-

CAS 55314-49-3 MFCD00065774

化学结构图

55314-49-3
SMILES: CCCCC[C@@H]1C=C[C@H]2[C@H](CC=CCCCC(=O)O1)[C@H](O)C[C@@H]2O |c:11,t:6,&1:5,8,9,19,22|

化学属性

Mol. FormulaC20H32O4
Mol. Weight336.52

别名和识别编码

Chemical NameProsta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-,lambda-lactone, (5Z,9-alpha,11-alpha, 13E,15S)-
CAS Number55314-49-3
Synonym Prostaglandin F2-alpha 1,15-lactone PGF2-alpha 1,15-lactone U 47473
Beilstein Registry Number1262372
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安全信息

RTECSUK8020600 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - hamster
DOSE                    : 800 ug/kg
SEX/DURATION            : female 4 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - female fertility index (e.g. # females pregnant
   per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 26,1089,1983

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Primate - monkey
DOSE                    : 4 mg/kg
SEX/DURATION            : female 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Maternal Effects - menstrual cycle changes or disorders
REFERENCE :
   PRGLBA Prostaglandins.  (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022)
   V.1-    1972-  Volume(issue)/page/year: 14,477,1977

系列性分类

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