(R)-(-)-Ibuprofen (S)-(+)-Lysinate

CAS 157369-85-2 MFCD07369460

化学结构图

157369-85-2
SMILES: CC(C)CC1=CC=C(C=C1)[C@@H](C)C(O)=O.NCCCC[C@H](N)C(O)=O |&1:10,20|

化学属性

Mol. Weight352
Mol. FormulaC19H32N2O4

别名和识别编码

CAS Number157369-85-2
Chemical Name(R)-(-)-Ibuprofen (S)-(+)-Lysinate
Synonym (?R)-
Chemical Name Translation
MDL NumberMFCD07369460
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分类

  • Chiral Reagents
  • Inhibitors
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • A nonsteroidal anti-inflammatory drug (NSAID). Optically active, selective cyclooxygenase inhibitor (IC50=14.9uM). Inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.

相关文献及参考

  • Busson, M., et al.: J. Int. Med Res., 14, 53 (1986),
  • Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993),
  • Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998),

系列性分类

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