Malonamic acid,N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo-(3.2.0)hept-6-yl)-2- phenyl-, 1-phenyl ester, sodiumsalt

CAS 21649-57-0 MFCD07793335

化学结构图

21649-57-0
SMILES: [Na+].CC1(C)S[C@@H]2[C@H](NC(=O)C(C3C=CC=CC=3)C(=O)OC3C=CC=CC=3)C(=O)N2[C@H]1C([O-])=O

化学属性

Mol. FormulaC23H21N2O6S.Na
Mol. Weight476.51

别名和识别编码

Chemical NameMalonamic acid,N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo-(3.2.0)hept-6-yl)-2- phenyl-, 1-phenyl ester, sodiumsalt
Wiswesser Line NotationT45 ANV ESTJ CMVYR&OVR& F1 F1 GVO &-NA-
Synonym Carboxybenzylpenicillin phenyl ester sodium salt Carbenicillin phenyl sodium Uticillin Sodium-alpha-phenoxycarbonylbenzylpenicillin Carfecilina sodica BRL 3475 Carfecillin sodium
CAS Number21649-57-0
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安全信息

RTECSON9110000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 10 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MDACAP Medicamentos de Actualidad.  (J.R. Prous, S.A., Apartado de Correos
   540, 08080 Barcelona, Spain)  V.1-    1965-  Volume(issue)/page/year:
   11,135,1975

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : >4 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,186,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3040 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ANTBAL Antibiotiki.  (Moscow, USSR)  V.1-29, 1956-84.  For publisher
   information, see AMBIEH.  Volume(issue)/page/year: 23,45

{hazard_com

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 572 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 717 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,186,1982

系列性分类

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