(2S,5R,6R)-6-((R)-2-(4-Ethyl-2,3-Dioxopiperazine-1-Carboxamido)-2-Phenylacetamido)-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylic Acid (2S,5R,6R)-6-((R)-2-(4-乙基-2,3-二氧代哌嗪-1-甲酰胺基)-2-苯基乙酰胺基)-3,3-二甲基-7-氧代-4-硫杂-1-氮杂双环[3.2.0]庚烷-2-羧酸

CAS 61477-96-1 MFCD00865043

化学结构图

61477-96-1
SMILES: CCN1CCN(C(=O)C1=O)C(=O)N[C@H](C1C=CC=CC=1)C(=O)N[C@H]1[C@H]2SC(C)(C)[C@H](C(O)=O)N2C1=O

化学属性

Mol. FormulaC23H27N5O7S
Mol. Weight518

别名和识别编码

Chemical Name(2S,5R,6R)-6-((R)-2-(4-Ethyl-2,3-Dioxopiperazine-1-Carboxamido)-2-Phenylacetamido)-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylic Acid
CAS Number61477-96-1
Synonym 6-(D-(-)-alpha-(4-Ethyl-2,3-dioxo-1-piperazinecarboxamido)phenylacetamido)penicillanic acid Piperacillin (2S,5R,6R)-
Chemical Name Translation(2S,5R,6R)-6-((R)-2-(4-乙基-2,3-二氧代哌嗪-1-甲酰胺基)-2-苯基乙酰胺基)-3,3-二甲基-7-氧代-4-硫杂-1-氮杂双环[3.2.0]庚烷-2-羧酸
MDL Number
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分类

  • Aromatics
  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Sulfur & Selenium Compounds

产品应用

  • Broad spectrum semi-synthetic antibiotic related to Penicillin. Antibacterial.

相关文献及参考

  • Takai, A., et al.: Chemotherapy, 25, 816 (1977),
  • Bodey, G.P., et al.: Antimicrob. Agents Chemother., 14, 78 (1978),
  • Kuck, N.A., et al.: J. Antibiot., 31, 1175 (1978),

安全信息

RTECSXH8952200
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YKKZAJ Yakugaku Zasshi.  Journal of Pharmacy.  (Nippon Yakugakkai, 2-12-15
   Shibuya, Shibuya-ku, Tokyo 150, Japan)  No.1-    1881-
   Volume(issue)/page/year: 97,987,1977

系列性分类


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