Ameltolide 4-氨基-N-(2,6-二甲基苯基)苯甲酰胺

CAS 787-93-9 MFCD00865288

化学结构图

787-93-9
SMILES: Cc1cccc(C)c1NC(=O)c1ccc(N)cc1

化学属性

Mol. FormulaC15H16N2O
Mol. Weight240.30
Melting Point220 - 222 °C
Boiling Point
Flash Point-

别名和识别编码

Chemical Name4-Amino-N-(2,6-Dimethylphenyl)Benzamide
CAS Number787-93-9
Alfabeta NameAMINODIMETHYLPHENYLBENZAMIDE N426()----,
MDL NumberMFCD00865288
Chemical Name Translation4-氨基-N-(2,6-二甲基苯基)苯甲酰胺
Synonym Ameltolide {LY} Ameltolide LY 201116 LY-201116 Lilly 201116 ameltolide ameltolide monohydrobromide ameltolide monohydrochloride ameltolide sulfate {} {LY} Ameltolide {} {} {LY} Ameltolide {} {} {} {LY} Ameltolide {} {} {} {} {LY} Ameltolide {} {} {} {} {} {LY} Ameltolide {} {} {} {} {} {} {PubChem} ADD 75073 {} {} {} {} {} {} {} {PubChem} 4-amino-N-(2,6-dimethylphenyl)benzamide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Ameltolide {} {} {} {} {} {} {} {} {} {} {LY} Ameltolide {} {} {} {} {} {} {} {} {} {} {} {LY} Ameltolide {} {} {} {} {} {} {} {} {} {} {} {} {LY} Ameltolide {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Ameltolide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Ameltolide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Ameltolide {} {} {} {} {} {} {} {} {} {} {} {} {}
Beilstein Registry Number2734562
LabNetwork Molecule IDLN00132766
PubChem Substance ID13086
InChIInChI=1S/C15H16N2O/c1-10-4-3-5-11(2)14(10)17-15(18)12-6-8-13(16)9-7-12/h3-9H,16H2,1-2H3,(H,17,18)
Canonical SMILESO=C(C1=CC=C(C=C1)N)NC2=C(C=CC=C2C)C
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安全信息

Warnings IRRITANT
RTECSDM5325000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 161 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EPILAK Epilepsia (New York).  (Raven Press, 1185 Ave. of the Americas, New
   York, NY 10036) Ser.1-3: 1909-55; Ser.4: V.1-    1959-
   Volume(issue)/page/year: 29,198,1988

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE                    : 1300 mg/kg
SEX/DURATION            : female 6-18 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   TJADAB Teratology, The International Journal of Abnormal Development. (Alan
   R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
   Volume(issue)/page/year: 44,37,1991

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 600 mg/kg
SEX/DURATION            : female 6-17 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   TJADAB Teratology, The International Journal of Abnormal Development. (Alan
   R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
   Volume(issue)/page/year: 44,37,1991

Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352
  • P304+P340
  • P305+P351+P338
  • P319
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P332+P317
  • P337+P317
  • P362+P364
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Storage condition -20 -20°C -20°C, Inert atmosphere

系列性分类


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