Phenothiazine,10-diethylaminopropionyl-3-trifluoromethyl-,hydrochloride

CAS 30223-48-4 MFCD00865445

化学结构图

30223-48-4
SMILES: CCN(CCC(=O)N1C2C=C(C=CC=2SC2C=CC=CC1=2)C(F)(F)F)CC

化学属性

Mol. FormulaC20H21F3N2OS
Mol. Weight394.49

别名和识别编码

Chemical NamePhenothiazine,10-diethylaminopropionyl-3-trifluoromethyl-,hydrochloride
Wiswesser Line NotationT C666 BN ISJ BV2N2&2 FXFFF &GH
Synonym 10-Diethylaminopropionyl-3-trifluoromethyl phenothiazine hydrochloride Fluoracizine
Beilstein Registry Number1229602
CAS Number30223-48-4
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安全信息

RTECSSO4700000
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 10 mg/kg
SEX/DURATION            : female 4 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   FATOAO Farmakologiya i Toksikologiya (Moscow).  For English translation, see
   PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-   
   1939-  Volume(issue)/page/year: 36,399,1973

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 10 mg/kg
SEX/DURATION            : female 4 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   RPTOAN Russian Pharmacology and Toxicology (English Translation).
   Translation of FATOAO.  (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey,
   UK)  V.30-    1967-  Volume(issue)/page/year: 36,178,1973

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rabbit
DOSE                    : 140 mg/kg
SEX/DURATION            : female 16-29 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   RPTOAN Russian Pharmacology and Toxicology (English Translation).
   Translation of FATOAO.  (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey,
   UK)  V.30-    1967-  Volume(issue)/page/year: 36,178,1973

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE                    : 140 mg/kg
SEX/DURATION            : female 16-29 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :

系列性分类


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