Pheniramine 非尼拉敏

CAS 86-21-5 MFCD00865659

化学结构图

86-21-5
SMILES: CN(C)CCC(c1ccccc1)c1ccccn1

化学属性

Mol. FormulaC16H20N2
Mol. Weight240

别名和识别编码

Chemical NamePheniramine
MDL NumberMFCD00865659
Chemical Name Translation非尼拉敏
Synonym 1-Phenyl-1-(2-pyridyl)-3-dimethylaminopropane 1-phenyl-1-(2-pyridyl)-3-dimethylaminopropane 2-(3-Dimethylamino-1-phenylpropyl)pyridine 2-(3-dimethylamino-1-phenylpropyl)pyridine 2-(alpha-(2-(dimethylamino)ethyl)benzyl)-pyridin 2-(alpha-(2-Dimethylaminoethyl)benzyl)pyridine 2-(alpha-(2-dimethylaminoethyl)benzyl)pyridine 2-Pyridinepropanamine, N,N-dimethyl-gamma-phenyl- 2-[alpha-[2-(Dimethylamino)ethyl]benzyl]pyridine 3-Phenyl-3-(2-pyridyl)-N,N-dimethylpropylamine 3-Phenyl-3-(2-pyridyl)-N,N-dimethylpropylanine 3-phenyl-3-(2-pyridyl)-n,n-dimethylpropylanine AVIL Avil Bimaleate, Pheniramine Daneral Feniramine Histapyridamine Maleate, Pheniramine Metron N,N-Dimethyl-3-phenyl-3-(2-pyridinyl)-1-p
CAS Number86-21-5
EC Number201-656-2
Wiswesser Line NotationT6NJ BYR&2N1&1
Beilstein Registry Number0192445
PubChem Substance ID4761
InChIInChI=1S/C16H20N2/c1-18(2)13-11-15(14-8-4-3-5-9-14)16-10-6-7-12-17-16/h3-10,12,15H,11,13H2,1-2H3
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安全信息

RTECSUS9625000
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 14 mg/kg
TOXIC EFFECTS :
   Behavioral - hallucinations, distorted perceptions
   Behavioral - muscle contraction or spasticity
REFERENCE :
   MJAUAJ Medical Journal of Australia.  (Australasian Medical Pub. Co. Ltd.,
   71-79 Arundel St., Glebe, N.S.W., Australia)  V.1-    1914-
   Volume(issue)/page/year: 2,110,1976

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 48 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
   Pharmakologie.  (Berlin, Ger.) V.110-253, 1925-66.  For publisher
   information, see NSAPCC.  Volume(issue)/page/year: 211,328,1950

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 30 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - other changes
   Endocrine - hyperglycemia
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
   Pharmakologie.  (Berlin, Ger.) V.110-253, 1925-66.  For publisher
   information, see NSAPCC.  Volume(issue)/page/year: 211,328,1950

Hazard statements
  • H300 Fatal if swallowed 吞食致命
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P301+P310
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P330 Rinse mouth. 漱口
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....

其他信息

  • MOL 文件:86-21-5.mol

系列性分类


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