Zardaverine

CAS 101975-10-4 MFCD00867059

化学结构图

101975-10-4
SMILES: COC1=CC(=CC=C1OC(F)F)C1C=CC(=O)NN=1

化学属性

Mol. FormulaC12H10F2N2O3
Mol. Weight268.22

别名和识别编码

Chemical NameZardaverine
Synonym 6-(4-Difluoromethoxy-3-methoxyphenyl)-3(2H)-pyridazinone Zardaverine
MDL NumberMFCD00867059
PubChem Substance ID24278784
CAS Number101975-10-4
Chemical Name Translation
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SNA} Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Cyclic Nucleotide Metabolism, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, G Proteins and Cyclic Nucleotides, P to Q, Phosphodiesterase III and IV, Phosphodiesterase Inhibitors, Z
  • {SNA} Cyclic Nucleotide Metabolism, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, G Proteins and Cyclic Nucleotides, P to Q, Phosphodiesterase III and IV, Phosphodiesterase Inhibitors, 生化试剂, 细胞信号转导和神经科学, 细胞生物学, 酶、抑制剂和底物

相关文献及参考

  • [2]. D. Ukena, K. Rentz, C. Reiber, et al. Effects of the mixed phosphodiesterase III/IV inhibitor, zardaverine, on airway function in patients with chronic airflow obstruction. Respiratory Medicine.1995, 89 ( 6) : 441-444.
  • [3]. Schade FU, Schudt C. The specific type III and IV phosphodiesterase inhibitor zardaverine suppresses formation of tumor necrosis factor by macrophages. European Journal of Pharmacology.1993, 230(1):9-14.
  • 1. Schudt, C., et al., Zardaverine as a selective inhibitor of phosphodiesterase isozymes Biochem. Pharmacol. 42 , 153-162, (1991)
  • Underwood, D.C., et al. J. Pharmacol. Exp. Ther. 270 , 250, (1994) 摘要
  • [1]. R.T. Schermuly, H. Leuchte, H.A. Ghofrani, et al. Zardaverine and aerosolised iloprost in a model of acute respiratoryfailure. ERJ, 2003 ,22 (2): 34
  • [1]. R.T. Schermuly, H. Leuchte, H.A. Ghofrani, et al. Zardaverine and aerosolised iloprost in a model of acute respiratoryfailure. ERJ, 2003 ,22 (2): 342-347.

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

系列性分类


相关产品推荐