19,24-Dinor-17-alpha-chola-1,3,5(10),7,20,22-hexaene-3,17-diol, 21,23-epoxy-, 3-acetate

CAS 10322-73-3 MFCD00867395

化学结构图

10322-73-3
SMILES: C[C@]12CC[C@@H]3C4C=CC(=CC=4CC=C3[C@@H]1CC[C@@]2(O)C1=COC=C1)OC(C)=O

化学属性

Mol. FormulaC24H26O4
Mol. Weight378.50

别名和识别编码

Chemical Name19,24-Dinor-17-alpha-chola-1,3,5(10),7,20,22-hexaene-3,17-diol, 21,23-epoxy-, 3-acetate
Synonym AY-11483 AY 11483-16 19,24-Dinorchola-1,3,5(10),7,20,22-hexaene-3,17-diol, 21,23-epoxy-,
CAS Number10322-73-3
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安全信息

RTECSJF7952000 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 17500 ug/kg
SEX/DURATION            : female 35 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - female fertility index (e.g. # females pregnant
   per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
   JRPFA4 Journal of Reproduction and Fertility.  (Biochemical Soc. Book Depot,
   POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK)  V.1-    1960-
   Volume(issue)/page/year: 18,509,1969

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 250 ug/kg
SEX/DURATION            : female 1-5 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
REFERENCE :
   JRPFA4 Journal of Reproduction and Fertility.  (Biochemical Soc. Book Depot,
   POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK)  V.1-    1960-
   Volume(issue)/page/year: 18,509,1969

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 200 ug/kg
SEX/DURATION            : female 4 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - other measures of fertility
REFERENCE :
   JRPFA4 Journal of Reproduction and Fertility.  (Biochemical Soc. Book Depot,
   POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK)  V.1-    1960-
   Volume(issue)/page/year: 18,509,1969

系列性分类

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