4-Amino-5-Chloro-2-Ethoxy-N-((4-(4-Fluorobenzyl)Morpholin-2-Yl)Methyl)Benzamide 4-氨基-5-氯-2-乙氧基-N-((4-(4-氟苄基)吗啉-2-基)甲基)苯甲酰胺
CAS 112885-41-3 MFCD00867430
化学结构图
SMILES: CCOC1=CC(N)=C(Cl)C=C1C(=O)NCC1CN(CC2=CC=C(F)C=C2)CCO1
化学属性
| Mol. Formula | C21H25ClFN3O3 |
|---|---|
| Mol. Weight | 421.90 |
别名和识别编码
| Chemical Name | 4-Amino-5-Chloro-2-Ethoxy-N-((4-(4-Fluorobenzyl)Morpholin-2-Yl)Methyl)Benzamide |
|---|---|
| CAS Number | 112885-41-3 |
| Alfabeta Name | AMINOCHLOROETHOXYFLUOROBENZYLMORPHOLINYLMETHYLBENZAMIDE N452442((()))----------- |
| MDL Number | MFCD00867430 |
| Synonym | 4-Amino-5-chloro-2-ethoxy-N-[[4-(4-fluorophenyl)methyl]-2-morpholinyl]methyl]benzamide Mosapid Mosid-MT Moza |
| Chemical Name Translation | 4-氨基-5-氯-2-乙氧基-N-((4-(4-氟苄基)吗啉-2-基)甲基)苯甲酰胺 |
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分类
- Agonist
- Amines
- Aromatics
- Pharmaceuticals
- Intermediates & Fine Chemicals,
产品应用
- A selective 5-HT4 receptor agonist. Gastroprokinetic.
相关文献及参考
- [2]. Curran MP, et al. Mosapride in gastrointestinal disorders. Drugs. 2008;68(7):981-91.
- [3]. Odaka T, et al. Serotonin 5- HT4 receptor agonist (mosapride citrate). Nihon Rinsho. 2006 Aug;64(8):1491-4.
- Ruth, M., et al.: Aliment Pharmacol. Ther., 12, 35 (1998),
- Yatera, S., et al.: Japan. Pharmacol. Ther., 21, 21 (1993),
- Yoshida, N., et al.: Arch. Int. Pharmacodyn. Ther., 300, 51 (1989),
- [1]. Tack J, et al. Systematic review: cardiovascular safety profile of 5-HT(4) agonists developed for gastrointestinal disorders. Aliment Pharmacol Ther. 2012 Apr;35(7):745-67.
- [1]. Tack J, et al. Systematic review: cardiovascular safety profile of 5-HT(4) agonists developed for gastrointestinal disorders. Aliment Pharmacol Ther. 2012 Apr;35(7):745-67.
- [2]. Curran MP, et al. Mosapride in gastrointestinal disorders. Drugs. 2008;68(7):981-91.
- [3]. Odaka T, et al. Serotonin 5- HT4 receptor agonist (mosapride citrate). Nihon Rinsho. 20
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