(R)-3-((S)-5-Oxopyrrolidine-2-Carbonyl)Thiazolidine-4-Carboxylic Acid (R)-3-((S)-5-氧代吡咯烷-2-羰基)噻唑烷-4-羧酸

CAS 121808-62-6 MFCD00867583

化学结构图

121808-62-6
SMILES: OC(=O)[C@@H]1CSCN1C(=O)[C@@H]1CCC(=O)N1

化学属性

Mol. FormulaC9H12N2O4S
Mol. Weight244.27

别名和识别编码

Chemical Name(R)-3-((S)-5-Oxopyrrolidine-2-Carbonyl)Thiazolidine-4-Carboxylic Acid
CAS Number121808-62-6
Synonym (4R)-3-[[(2S)-5-oxo-2-pyrrolidinyl]carbonyl]-4-thiazolidinecarboxylic Acid Polimod Adimod Axil (R)-3-((S)-(5-Oxo-2-pyrrolidinyl)carbonyl)-thiazolidin-4-carbonsaeure (R-(R*,S*))-3-((5-Oxo-2-pyrrolidinyl)carbonyl)-4-thiazolidinecarboxylic Onaka
Beilstein Registry Number6636310
Reaxys-RN6636310
Chemical Name Translation(R)-3-((S)-5-氧代吡咯烷-2-羰基)噻唑烷-4-羧酸
MDL NumberMFCD00867583
PubChem Substance ID253661767
Merck Number7419
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分类

  • Chiral Reagents
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Sulfur & Selenium Compounds

产品应用

  • Immunostimulant used in patients with cell-mediated immunodepression.

相关文献及参考

  • Gu, C., et al.: Pharm. Res., 25, 979 (2008),

安全信息

RTECSXJ5426675 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >4 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 44,1448,1994

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >4 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 44,1448,1994

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 44,1448,1994

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >8 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 44,1448,1994

系列性分类

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