2-Methoxy Promazine

CAS 61-01-8 MFCD00867753

化学结构图

61-01-8
SMILES:

化学属性

Mol. FormulaC18H22N2OS
Mol. Weight314.48

别名和识别编码

Chemical NamePhenothiazine, 10-(3-(dimethylamino)propyl)-2-methoxy
CAS Number61-01-8
Synonym 2-Methoxy-10-(3'-dimethylaminopropyl)phenothiazine Methopromazine Mopazine Mopazin 2-Methoxypromazine Neoproma 10-(3-Dimethylaminopropyl)-2-methoxyphenothiazine Methoxypromazine Tentone 10-[3-(Dimethylamino)propyl]-2-methoxyphenothiazine Tenton 2-Methoxy-N,N-dimethyl-10H-phenothiazine-10-propanamine RP 4632 2-Methoxy-10-(3'-
Chemical Name Translation
Wiswesser Line NotationT C666 BN ISJ B3N1&1 EO1
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分类

  • Amines
  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Sulfur & Selenium Compounds

产品应用

  • A Promazine

相关文献及参考

  • Merville M.P., et al.: J. Biol. Chem., 259, 15069 (1984),

安全信息

RTECSSO7600000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 95 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 125,101,1960

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 408 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 125,101,1960

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 112 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 125,101,1960

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 730 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 125,101,1960

系列性分类

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