Phenothiazine,10-(2-(1-methyl-2-piperidyl)ethyl)-2-methylsulfonyl-,

CAS 14759-06-9 MFCD00867758

化学结构图

14759-06-9
SMILES: CN1CCCCC1CCN1C2C=C(C=CC=2SC2C=CC=CC1=2)S(C)(=O)=O

化学属性

Mol. FormulaC21H26N2O2S2
Mol. Weight403

别名和识别编码

Chemical NamePhenothiazine,10-(2-(1-methyl-2-piperidyl)ethyl)-2-methylsulfonyl-,
CAS Number14759-06-9
Synonym Inofal Sulforidazine TPN-12 10-(2-(1-Methyl-2-piperidyl)ethyl)-2-methylsulfonylphenothiazine 10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylsulfonyl)- Imagotan Psychoson
Wiswesser Line NotationT C666 BN ISJ ESW1 B2- BT6NTJ A1
Beilstein Registry Number1230366
Chemical Name Translation
MDL Number
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分类

  • Heterocycles
  • Metabolites & Impurities
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Sulfur & Selenium Compounds

产品应用

  • A major metabolite of Thioridazine (THD 2-SO2).

相关文献及参考

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安全信息

RTECSSP1925000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 24 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,53,1972

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 29 mg/kg
TO

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,53,1972

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 138 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 20,159

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 29 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,53,1972

系列性分类

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