Iopamidol 碘帕醇

CAS 60166-93-0 MFCD00867931

化学结构图

60166-93-0
SMILES: C[C@H](O)C(=O)NC1C(I)=C(C(I)=C(C=1I)C(=O)NC(CO)CO)C(=O)NC(CO)CO

化学属性

Mol. FormulaC17H22I3N3O8
Mol. Weight777

别名和识别编码

Chemical NameIopamidol
CAS Number60166-93-0
Synonym Niopam N,N?-Bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[[(2S)-2-hydroxy-1-oxopropyl]amino]-2,4,6-triiodo-1,3-benzenedicarboxamide B-15000 Iopamiron Isovue SQ-13396 L-(+)-N,N'-Bis(2-hydroxy-1-hydroxymethylethyl)-2,4,6-triiodo-5-lactamide So Iopamiro Iomapidol Jopamiro
Chemical Name Translation碘帕醇
Wiswesser Line NotationQ1Y1QMVR BI DI FI CMVYQ1 EVMY1Q1Q
Beilstein Registry Number6250226
MDL NumberMFCD00867931
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分类

  • Diagnostic
  • Pharmaceuticals
  • Intermediates & Fine Chemicals,

产品应用

  • Nonionic radiocontrast medium. Diagnostic aid (radiopaque medium).

相关文献及参考

  • Drayer, B., et al.: Am. J. Neuroradiol., 3, 59 (1982),
  • Molyneux, A.J., et al.: Br. J. Radiol., 55, 117 (1982),
  • Sovak, M., et al.: Radiology, 142, 115 (1982),

安全信息

RTECSCZ2235000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intracerebral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2449 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 45,200,1995

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 20 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 32,835,1977

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 22044 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARASA5 Acta Radiologica, Supplementum.  (Acta Radiologica, POB 7449, S-10391
   Stockholm, Sweden) No.1-    1921-  Volume(issue)/page/year: 370,41,1987

TYPE OF TES

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraarterial
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 13268 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4001323

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Ro

系列性分类

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