2(1H)-Pyridone, 1-(m-aminophenyl)-

CAS 134-37-2 MFCD00868033

化学结构图

134-37-2
SMILES: Nc1cccc(-n2ccccc2=O)c1

化学属性

Mol. FormulaC11H10N2O
Mol. Weight186.23

别名和识别编码

Chemical Name2(1H)-Pyridone, 1-(m-aminophenyl)-
Synonym 1-(3-Aminophenyl)-2-(1H)-pyridinone 1-(3-Aminophenyl)-2-pyridone Dornwall Amphenidone 1-m-Aminophenyl-2-pyridone Aminophenylpyridone Dornwal 1-(m-Aminofenylo)-2-pirydonu
Wiswesser Line NotationT6NVJ AR CZ
CAS Number134-37-2
Beilstein Registry Number1526918
PubChem Substance ID8641
InChIInChI=1S/C11H10N2O/c12-9-4-3-5-10(8-9)13-7-2-1-6-11(13)14/h1-8H,12H2
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安全信息

RTECSUV1146000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APPHAX Acta Poloniae Pharmaceutica.  For English translation, see APPFAR.
   (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland)  V.1-    1937-
   Volume(issue)/page/year: 20,155,1963

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2300 mg/kg
TOXIC EFFECTS :
   Behavioral - sleep
   Behavioral - muscle weakness
   Behavioral - ataxia
REFERENCE :
   FEPRA7 Federation Proceedings, Federation of American Societies for
   Experimental Biology. (Bethesda, MD)  V.1-46, 1942-87.
   Volume(issue)/page/year: 19,390,1960

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1300 mg/kg
TOXIC EFFECTS :
   Behavioral - sleep
   Behavioral - muscle weakness
   Behavioral - ataxia
REFERENCE :
   FEPRA7 Federation Proceedings, Federation of American Societies for
   Experimental Biology. (Bethesda, MD)  V.1-46, 1942-87.
   Volume(issue)/page/year: 19,390,1960

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 565 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APPHAX Acta Poloniae Pharmaceutica.  For English translation, see APPFAR.
   (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland)  V.1-    1937-
   Volume(issue)/page/year: 20,155,1963

系列性分类


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