Cyclotetrasiloxane, 2,6-diphenylhexamethyl-, Z-

CAS 33204-76-1 MFCD00868586

化学结构图

33204-76-1
SMILES: C[Si]1(C)O[Si](C)(O[Si](C)(C)O[Si](C)(O1)C1C=CC=CC=1)C1C=CC=CC=1

化学属性

Mol. FormulaC18H28O4Si4
Mol. Weight420.82

别名和识别编码

Chemical NameCyclotetrasiloxane, 2,6-diphenylhexamethyl-, Z-
Wiswesser Line NotationT8-SI-O-SI-O-SI-O-SI-OJ A1 A1 C1 CR& E1 E1 F1 FR
Synonym Cisobitan Quadrosilan 2,6-cis-Diphenylhexamethylcyclotetrasiloxane cis-2,6-Diphenyl-2,4,4,6,8,8-hexamethylcyclotetrasiloxane Cyclic 2,6-cis-diphenylhexamethylcyclotetrasiloxane KABI 1774 Cyclotetrasiloxane, 2,6-diphenyl-2,4,4,6,8,8-hexamethyl-, (Z)- Cyclotetrasiloxane, 2,2,4,6,6,8-hexamethyl-4,8-diphenyl-, cis-
CAS Number33204-76-1
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安全信息

RTECSGZ4390000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APTSAI Acta Pharmacologica et Toxicologica, Supplementun.  (Munksgaard
   International Pub., POB 2148, DK-1016 Copenhagen K, Denmark)  No.1- 1947- 
   Volume(issue)/page/year: 36(3),93,1975

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APTSAI Acta Pharmacologica et Toxicologica, Supplementun.  (Munksgaard
   International Pub., POB 2148, DK-1016 Copenhagen K, Denmark)  No.1- 1947- 
   Volume(issue)/page/year: 36(3),93,1975

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 1 mg/kg
SEX/DURATION            : female 1 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - female fertility index (e.g. # females pregnant
   per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
   BIREBV Biology of Reproduction.  (Soc. for the Study of Repr

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TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 10 mg/kg
SEX/DURATION            : female 5 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   BIREBV Biology of Reproduction.  (Soc. for the Study of Reproduction, 309 W.
   Clark St., Champaign, IL 61820)  V.1-    1969-  Volume(issue)/page/year:
   7,260,1972

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Primate - monkey
DOSE                    : 280 mg/kg
SEX/DURATION            : male 28 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
   APTSAI Acta Pharmacologica et Toxicologica, Supplementun.  (Munksgaard
   International Pub., POB 2148, DK-1016 Copenhagen K, Denmark)  No.1- 1947- 
   Volume(issue)/page/year: 36(3),81,1975

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 3 mg/kg
SEX/DURATION            : female 1 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - other measures of fertility
REFERENCE :

TYPE OF TEST            : TDLo - Lowest published

系列性分类

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