8-chloro-1-phenyl-1h-1,5-benzodiazepine-2,4(3h,5h)-dione 8-chloro-1-phenyl-1h-1,5-benzodiazepine-2,4(3h,5h)-dione

CAS 22316-55-8 MFCD00871860

化学结构图

22316-55-8
SMILES: O=C1CC(=O)NC2C=CC(Cl)=CC=2N1C1C=CC=CC=1

化学属性

Mol. FormulaC15H11ClN2O2
Mol. Weight286.73

别名和识别编码

Chemical Name8-chloro-1-phenyl-1h-1,5-benzodiazepine-2,4(3h,5h)-dione
CAS Number22316-55-8
Synonym N-Desmethylclobazam N-Demethylclobazam 7-Chloro-5-phenyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione Clofazin Desmethylclobazam Norclobazam Demethylclobazam 8-Chloro-1-phenyl-
Chemical Name Translation8-chloro-1-phenyl-1h-1,5-benzodiazepine-2,4(3h,5h)-dione
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分类

  • Aromatics
  • Heterocycles
  • Metabolites & Impurities
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • The major metabolite of Clobazam

相关文献及参考

  • Bardy, A., et al.: Brain Develop., 13, 174 (1991),
  • Patsalos, P., et al.: Epilepsia, 43, 365 (2002),
  • Venisse, N., et al.: J. Anal. Toxicol., 27, 7 (2003),

安全信息

RTECSDE9600625 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >2583 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #3760074

系列性分类

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