7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone 7-[4-[4-(2,3-二氯苯基)-1-哌嗪基]丁氧基]-3,4-二氢-2(1H)-喹啉酮

CAS 129722-12-9 MFCD00892072

化学结构图

129722-12-9
SMILES: [2H]C([2H])(N1CCN(CC1)C1=CC=CC(Cl)=C1Cl)C([2H])([2H])C([2H])([2H])C([2H])([2H])OC1=CC=C2CCC(=O)NC2=C1

化学属性

Mol. FormulaC23H27Cl2N3O2
Mol. Weight448.39
Melting Point147.0 to 151.0 deg-C

别名和识别编码

Chemical Name7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone
CAS Number129722-12-9
Alfabeta NameARIPIPRAZOLE
MDL NumberMFCD00892072
Chemical Name Translation7-[4-[4-(2,3-二氯苯基)-1-哌嗪基]丁氧基]-3,4-二氢-2(1H)-喹啉酮
Synonym 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone 7-{4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy}-3,4-dihydro-2(1H)-quinolinone
Reaxys-RN7951706
Merck Number785
PubChem Substance ID160871264
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相关文献及参考

  • [2]. Burris KD, Molski TF, Xu C et al. Aripiprazole, a novel antipsychotic, is a high-affinity partial agonist at human dopamine D2 receptors. J Pharmacol Exp Ther. 2002 Jul;302(1):381-9.
  • [3]. Swainston Harrison T, Perry CM. Aripiprazole: a review of its use in schizophrenia and schizoaffective disorder. Drugs. 2004;64(15):1715-36.
  • [4]. Nagasaka Y, Oda K, Iwatsubo T, Kawamura A, Usui T.
  • Biopharm Drug Dispos. 2012 Jul 27. doi: 10.1002/bdd.1801.
  • Effects of aripiprazole and its active metabolite dehydroaripiprazole on the activities of drug efflux transporters expressed both in the intestine and at the blood-brain barrier.
  • Effects of aripiprazole and its active metabolite dehydroaripiprazole on the activities of drug efflux transporters expressed both in the intestine and at the blood-brain barrier.
  • Nagasaka Y, Oda K, Iwatsubo T, Kawamura A, Usui T.
  • Nagasaka Y, Oda K, Iwatsubo T, Kawamura A, Usui T.
  • [1]. Stip E, Tou

安全信息

Warnings IRRITANT
GHS Symbol
Signal word Warning
WGK Germany3
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
  • P301+P312+P330
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H302 Harmful if swallowed 吞食有害
RTECSVC8275950

系列性分类

  1. Medical Research Areas
  2. GPCR & G Protein
  3. 5-HT Receptor  (5-羟色胺受体)

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