Bryostatin 1

CAS 83314-01-6 MFCD00893832

化学结构图

83314-01-6
SMILES: CC(=O)O[C@H]1C[C@H]2C[C@@H](O)CC(=O)O[C@H](C[C@@H]3C/C(=C\C(=O)OC)/[C@H](OC(=O)/C=C/C=C/CCC)[C@@](O)(O3)C(C)(C)C=C[C@H]3C/C(/C[C@@H](C[C@](O)(O2)C1(C)C)O3)=C\C(=O)OC)[C@@H](C)O |t:42|

化学属性

Mol. FormulaC47H68O17
Mol. Weight905.03
TSCANo
Melting Point230-235°

别名和识别编码

Chemical NameBryostatin 1
MDL NumberMFCD00893832
PubChem Substance ID24891991
CAS Number83314-01-6
Merck Number14,1457
Synonym Bryostatin 1
Beilstein Registry Number4349157
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分类

  • {SNA} B, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Kinase/Phosphatase Biology, Protein Kinase Activators, Protein Kinase C (PKC), Serine/Threonine Kinase Activators, Serine/Threonine Kinase Biology
  • {SNA} B, Bioactive Small Molecule Alphabetical Index, Kinase/Phosphatase Biology,

相关文献及参考

  • Jurgen, E., et al. Mol. Pharmacol. 57 , 1224, (2000)
  • Song, X.D., et al. J. Biol. Chem. 274 , 1677, (1999)
  • Merck 14 ,1457

安全信息

RTECSEH9455000
WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter 
TYPE OF TEST            : Unscheduled DNA synthesis
ROUTE OF EXPOSURE       : Administration onto the skin
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 400 nmol/kg
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 9,555,1988

Hazard Codes Xn
Safety Statements
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
Risk Statements
  • R68 Possible risk of irreversible effects 可能有不可挽回的作用的危险

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Kinase/Phosphatase Biology - Cell Signaling and Neuroscience
  5. Serine/Threonine Kinase Biology - Kinase/Phosphatase Biology
  6. Serine/Threonine Kinase Activators - Serine/Threonine Kinase Biology
  7. Protein Kinase C (PKC) - Serine/Threonine Kinase Activators

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