Tigecycline 替加环素

CAS 220620-09-7 MFCD00935753

化学结构图

220620-09-7
SMILES: CC(C)(C)NCC(=O)NC1C=C(C2C[C@@H]3C[C@@H]4[C@H](C(O)=C(C(=O)[C@]4(O)C(O)=C3C(=O)C=2C=1O)C(N)=O)N(C)C)N(C)C |&1:14,16,17,23|

化学属性

Mol. FormulaC29H39N5O8
Mol. Weight585.66
Melting Point180-183

别名和识别编码

Chemical NameTigecycline
CAS Number220620-09-7
Synonym tigecycline
MDL NumberMFCD00935753
Chemical Name Translation替加环素
Reaxys-RN8379453
Merck Number9432
PubChem Substance ID354335260
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分类

  • Amines
  • Chiral Reagents
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • A glycylcycline antibiotic, used to treat infection by drug resistant bacteria such as Staphylococcus aureus (Staph aureus) and Acinetobacter baumannii.

相关文献及参考

  • Lim, T., et al.: J. Antibiotics, 62, 675 (2009),
  • Presterl, E., et al.: Antimicrob. Agents Chemother., 53, 3205 (2009),
  • Varma, M., et al.: J. Med. Chem., 52, 4844 (2009),

安全信息

GHS Symbol
Safety Statements
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前，切勿操作。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P305+P351+P338
  • P305+P351+P338+P310
  • P308+P313
  • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
UN Number 3077
Hazard Codes
Signal word
WGK Germany3
Packing GroupIII
Hazard Class9
Hazard statements
  • H318 Causes serious eye damage 严重伤害眼睛
RTECSQI7619500
Storage condition <0°C

系列性分类

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