1-((2-Chlorophenyl)Diphenylmethyl)-1H-Pyrazole 1-((2-氯苯基)二苯基甲基)-1H-吡唑

CAS 289905-88-0 MFCD09842562

化学结构图

289905-88-0
SMILES: ClC1C=CC=CC=1C(C1C=CC=CC=1)(C1C=CC=CC=1)N1C=CC=N1

化学属性

Mol. FormulaC22H17ClN2
Mol. Weight345
TSCANo
Melting Point145-147°

别名和识别编码

Chemical Name1-((2-Chlorophenyl)Diphenylmethyl)-1H-Pyrazole
CAS Number289905-88-0
Synonym 1-(2-Chlorophenyl)diphenyl)methyl]-1H-pyrazole 1-[(2-Chlorophenyl)diphenylmethyl]-1H-pyrazole TRAM-34
MDL NumberMFCD09842562
Chemical Name Translation1-((2-氯苯基)二苯基甲基)-1H-吡唑
PubChem Substance ID329826852
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分类

  • Heterocycles
  • {SNA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Ion Channels, Monovalent Ion Channels, Potassium Channel Modulators, T, Voltage-gated Ion Channels
  • Inhibitors
  • {SNA} Bioactive Small Molecule Alphabetical Index, Ion Channels, Monovalent Ion Channels, Potassium Channel Modulators, T, Voltage-gated Ion Channels, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学

产品应用

  • TRAM-34 blocks intermediate conductance calcium-activated potassium channel IKCa1 with a Kd of 20nM and exhibits exquisite selectivity for the channel. Clotrimazole impurity.

相关文献及参考

  • Wulff, H., et al.: J. of Biological Chemistry, 276, 34, 32040 (2001)

安全信息

GHS Symbol
Hazard statements
  • H413 Maycauselonglastingharmfuleffectstoaquaticlife 可能对水生生物造成长期持续有害影响。
  • H302 Harmful if swallowed 吞食有害
WGK Germany3
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes Xn
Risk Statements
  • R22 Harmful if swallowed 吞咽有害

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Bioactive Small Molecules - Cell Biology
  4. T - Bioactive Small Molecules

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