(4R,5R,7R,10S,13R)-13-Carbamoyl-4-Formyl-7,10-Dimethyl-2,8,11-Trioxo-5-((1R,2R)-1,2,3-Trihydroxypropyl)-6-Oxa-3,9,12-Triazahexadecan-16-Oic Acid (4R,5R,7R,10S,13R)-13-氨基甲酰基-4-甲酰基-7,10-二甲基-2,8,11-三氧代-5-((1R,2R)-1,2,3-三羟丙基)-6-氧杂-3,9,12-三氮杂十六烷-16-酸

CAS 53678-77-6 MFCD00077638

化学结构图

53678-77-6
SMILES: CC(=O)N[C@@H]1[C@@H](O[C@H](C)C(=O)N[C@@H](C)C(=O)N[C@H](CCC(O)=O)C(N)=O)[C@H](O)[C@@H](CO)OC1O

化学属性

Mol. FormulaC19H32N4O11· xH2O
Mol. Weight492.48 (anhydrous basis)

别名和识别编码

Chemical Name(4R,5R,7R,10S,13R)-13-Carbamoyl-4-Formyl-7,10-Dimethyl-2,8,11-Trioxo-5-((1R,2R)-1,2,3-Trihydroxypropyl)-6-Oxa-3,9,12-Triazahexadecan-16-Oic Acid
Synonym Adjuvant Peptide Muramyl dipeptide Muramyl dipeptide N(sup 2)-(N-(N-Acetylmuramoyl)-L-alanyl)-D-alpha-glutamine N-Acetylmuramyl-L-alanyl-D-isoglutamine hydrate
MDL NumberMFCD00077638
PubChem Substance ID24891464
Beilstein Registry Number4220745
CAS Number53678-77-6
EC Number258-696-9
Chemical Name Translation(4R,5R,7R,10S,13R)-13-氨基甲酰基-4-甲酰基-7,10-二甲基-2,8,11-三氧代-5-((1R,2R)-1,2,3-三羟丙基)-6-氧杂-3,9,12-三氮杂十六烷-16-酸
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分类

  • Bacteria-derived adjuvants, Cell Biology, Cell Culture, Cell Signaling and Neuroscience, Other Peptides, Peptides and Proteins, Peptides for Cell Biology, Vaccine Adjuvants, Vaccine Production
  • {SNA} Bacteria-derived adjuvants, Other Peptides, Peptides and Proteins, Peptides for Cell Biology, Vaccine Adjuvants, 疫苗生产, 细胞信号转导和神经科学, 细胞培养, 细胞生物学
  • {SNA} Bacteria-derived adjuvants, Cell Biology, Cell Culture, Cell Signaling and Neuroscience, Other Peptides, Peptides and Proteins, Peptides for Cell Biology, Vac

相关文献及参考

  • Lefancier, P., et al. Int. J. Pept. Protein Res. 9 , 249, (1977)
  • Ellouz, F., et al. Biochem. Biophys. Res. Commun. 59 , 1317, (1974)
  • Chedid, L. and Lederer, E. Biochem. Pharmacol. 27 , 2183, (1978)
  • Merck 14 ,6305

安全信息

WGK Germany3
RTECSMA2275260
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intratesticular
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 800 ug/kg
SEX/DURATION            : male 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
   sperm morphology, motility, and count)
REFERENCE :
   IJMRAQ Indian Journal of Medical Research.  (Indian Council of Medical
   Research, Ansari Nagar, New Delhi 110 029, India)  V.1-    1913-
   Volume(issue)/page/year: 74,251,1981

系列性分类


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