Teijin compound 1 hydrochloride

CAS N/A MFCD16618399

化学结构图

N/A
SMILES:

化学属性

Mol. Weight476.32
Mol. FormulaC21H21ClF3N3O2·HCl

别名和识别编码

Synonym N-[2-[[(3R)-1-[(4-chlorophenyl)methyl]-3-pyrrolidinyl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamide hydrochloride
MDL NumberMFCD16618399
Chemical NameTeijin compound 1 hydrochloride
PubChem Substance ID329826865
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分类

  • {SA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Chemokine Inhibitors, Chemokines, Cytokines and Growth Factors, Cytokines, Growth Factors and Hormones, T
  • {SNA} Bioactive Small Molecule Alphabetical Index, Chemokine Inhibitors, Chemokines, Cytokines and Growth Factors, Cytokines, Growth Factors and Hormones, T, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学

相关文献及参考

  • Hall, S.E., et al., Elucidation of binding sites of dual antagonists in the human chemokine receptors CCR2 and CCR5. Mol. Pharmacol. 75 , 1325-1336, (2009) 摘要
  • Moree, W. J., et al., Potent antagonists of the CCR2b receptor. Part 3: SAR of the (R)-3-aminopyrrolidine series Bioorg. Med. Chem. Lett. 18 , 1869-1873, (2008)
  • Moree, W.J., et al., Small molecule antagonists of the CCR2b receptor. Part 2: Discovery process and initial structure-activity relationships of diamine derivatives. Bioorg. Med. Chem. Lett. 14th ed.,, 5413-5416, (2004)

安全信息

WGK Germany3

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Cytokines, Growth Factors and Hormones - Cell Signaling and Neuroscience
  5. Cytokines and Growth Factors - Cytokines, Growth Factors and Hormones
  6. Chemokines - Cytokines and Growth Factors
  7. Chemokine Inhibitors - Chemokines

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