Phenyl dichlorophosphate 二氯化磷酸苯酯

CAS 770-12-7 MFCD00002067

化学结构图

770-12-7
SMILES: O=P(Cl)(Cl)Oc1ccccc1

化学属性

Mol. FormulaC6H5Cl2O2P
Mol. Weight211
Density1.412
Refractive index1.5220 to 1.5250
Boiling Point240°C(lit.)
Flash Point112°(233°F)
TSCAYes
Melting Point-1°C
Solubility分解
Stability对湿度敏感
Appearance 白色晶体，熔点 158-165℃，水溶性 40.4g/100mL 无色液体。沸点130-132℃（2.7kPa）。

别名和识别编码

Chemical NamePhenyl dichlorophosphate
Synonym PHENYLPHOSPHONIC ACID Dich Phosphorodichloridic acid phenyl ester { PHENYLPHOSPHORYL DICHLOR Dichlorphenylphosphat PHENYLP PHENYL PHOSPHORODICHLORIDATE Phenyldichlorphosphat DICHLOROPHOSPHORIC ACID PHENYL ESTER 二氯化磷酸苯酯 苯基磷二氯化物 苯氧基磷酰二氯 phenoxyphosphoryldichloride Phenyl dichloridophosphate dichlorophenoxyphosphineoxide PHENYL DICHLOROPHOSPHATE 二氯化磷酸苯酯 Phosphoroyl dichloride phenyl ester Phosphorsäure-monophenylesterdichlorid Phen Dichlorop phosphorodichloridicacid,phenylester phenoxydichlorophosphineoxide Phenyl dichlorophosphate phenylp PPOA 苯基二氯磷酸酯;苯基
MDL NumberMFCD00002067
CAS Number770-12-7
EC Number212-220-6
Beilstein Registry Number6,179
PubChem Substance ID87574455
Reaxys-RN511863
Merck Number7282
Chemical Name Translation二氯化磷酸苯酯
LabNetwork Molecule IDLN00226564
InChIInChI=1S/C6H5Cl2O2P/c7-11(8,9)10-6-4-2-1-3-5-6/h1-5H
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {uni_hamburg} no charge; carbocycle; aromatic; 6RingOnly; 6ring; 1fragment
  • {SNA} Building Blocks, Chemical Synthesis, Organic Building Blocks, Phosphorus Compounds, Phosphorus Halides

产品应用

  • 用于磷酸二酯的制备

相关文献及参考

  • In combination with NaI, cleaves dialkyl ethers to iodides in high yield: Synth. Commun., 18, 119 (1988), and 1,3-dithianes and other dithioacetals to carbonyl groups: Tetrahedron Lett., 29, 5471 (1988).
  • Reagent for the preparation of phosphate diesters. The phenyl group is removable by hydrogenolysis: J. Am. Chem. Soc., 75, 4510 (1953).
  • Short: III/39
  • Short: IV/20A
  • Short: III/20b
  • For a brief feature on uses of the reagent in synthesis, see: Synlett, 1651 (2004).
  • Reacts with the Li enolates of ß-diketones, in the presence of LiCl, to give ß-chloro-ɑß-enones: Can. J. Chem., 64, 520 (1986).
  • In combination with Dimethyl­ sulfoxide, A13280, effects selective oxidation of alcohols to aldehydes or ketones with less ɑ-chlorination than the more usual Swern (Oxalyl­ chloride, A18012) system: J. Org. Chem., 52, 5621 (1987). Similarly, benzylamines have been converted to benzaldehydes: Synth. Commun., 19, 3407 (1989).
  • Merck: 14,7282 Beilstein:6,179
  • Merck: 14,7282
  • Coupling reagent, e.g. in pyridine for the preparation of derivatives of sulfinic acids with alcohols, amines, thiols etc.: Synthesis, 937 (1980). Similarly, carboxylic acids in pyridine can be coupled with thiols to give thiocarboxylic acid S-esters: Can. J. Chem., 58, 2645 (1980), and with sodium azide in the presence of a phase-transfer catalyst to give acyl azides: Synth. Commun., 13, 289 (1983).

安全信息

Signal word
GHS Symbol
WGK Germany3
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后，立即用大量…（由生产厂家指定）冲洗；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
Risk Statements
  • R37 Irritating to respiratory system 刺激呼吸道
  • R34 Causes burns 会导致灼伤
Precautionary statements
  • P303+P361+P353+P310+P363
  • P390 Absorb spillage to prevent material damage. 吸收溢出物，防止重大损害。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P330+P331
  • P405 Store locked up. 上锁保管。
  • P234 Keep only in original container. 只保留在原来的容器中。
  • P304+P340+P310
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P406 Store in corrosive resistant/… container with a resistant inner liner. 存放在耐腐蚀/具有耐性的内衬容器。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
  • P305+P351+P338+P310
  • P301+P330+P331+P310
Hazard statements
  • H290 May be corrosive to metals 可能腐蚀金属。
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
Personal Protective Equipment Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECSTD4393000
Packing GroupII
UN Number UN2922 1760 UN 3265 8/PG 2 3265
Storage condition Moisture Sensitive 充氩保存 2-8°C
Hazard Codes C
Hazard Class8 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 850 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 39(4),86,1974

其他信息

  • Sigma Aldrich:1571-33-1(sigmaaldrich)
  • TCI Shanghai:苯基二氯磷酸酯 Phenyl Dichlorophosphate,>;98.0%(GC)(T)(770-12-7)
  • TCI Shanghai:苯基膦酸 Phenylphosphonic Acid,>;98.0%(T)(1571-33-1)
  • 图谱信息:二氯化磷酸苯酯(770-12-7)质谱(MS) 二氯化磷酸苯酯(770-12-7)核磁图( 13 CNMR) 二氯化磷酸苯酯(770-12-7)红外图谱(IR1) 二氯化磷酸苯酯(770-12-7)核磁图( 1 HNMR)
  • F:10
  • 检测方法:GC,NMR
  • 海关编码:29209085
  • Alfa Aesar:苯基磷二氯化物,97% Phenyl phosphorodichloridate, 97%(770-12-7)
  • 用途一:苯膦酸类化合物大量用于农药生产，新开发的用途是作为防污涂料的中间体，用于制造阴燃剂、催化剂等。
  • 二氯化磷酸苯酯价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 C130480250 二氯磷酸苯 25g 558元 2011/04/16 P0209 二氯磷酸苯酯 Phenyl Dichlorophosphate 500G 2570元 2011/04/16 P0209 二氯磷酸苯酯 Phenyl Dichlorophosphate 25G 298元
  • 图谱信息:苯膦酸(1571-33-1)红外图谱(IR2) 苯膦酸(1571-33-1)Raman光谱 苯膦酸(1571-33-1)质谱(MS) 苯膦酸(1571-33-1)红外图谱(IR1)
  • MOL 文件:1571-33-1.mol
  • 下游产品:丙溴磷
  • MSDS 信息:Phenyl phosphorodichloridate(770-12-7).msds
  • Alfa Aesar:苯基磷酸,98+% Phenylphosphonic acid, 98+%(1571-33-1)
  • MSDS 信息:Phenylphosphonic acid(1571-33-1).msds
  • Acros Organics:苯基二氯磷酸酯 Phenyl dichlorophosphate, 99%(770-12-7)
  • 苯膦酸价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 P0204 苯基膦酸 Phenylphosphonic Acid 25G 150元 2014/06/02 P0204 苯基膦酸 Phenylphosphonic Acid 500G 1350元 2010/06/21 130790025 苯膦酸 Phenylphosphonic acid 98% 2.5 KG 4502元
  • 上游原料:苯膦酰二氯
  • 用途一:用作甲氨基阿维菌素苯甲酸盐合成专用催化剂
  • 下游产品:
  • Acros Organics:苯基膦酸 Phenylphosphonic acid, 98%(1571-33-1)
  • Sigma Aldrich:770-12-7(sigmaaldrich)
  • 方法一:由苯膦酰二氯水解得到。
  • 存储注意事项:湿度敏感
  • 敏感性:Moisture Sensitive
  • MOL 文件:770-12-7.mol

系列性分类

  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Carbonyl Compounds 羰基化合物
  5. Esters - Carbonyl Compounds
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Phosphorus Compounds 磷化合物
  5. Phosphonic/Phosphinic Acids - Phosphorus Compounds
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Phosphorus Compounds 磷化合物
  5. Phosphorus Halides - Phosphorus Compounds
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Phosphorus Compounds 磷化合物
  5. Phosphorus Halides - Phosphorus Compounds
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Phosphorus Compounds 磷化合物
  5. Phosphoramidites
  1. Functional Group 官能团索引
  2. phosphonic acid derivative
  1. Functional Group 官能团索引
  2. phosphonic acid
  1. Life Science 生命科学
  2. Biochemistry / Glyco-Chemistry
  3. DNA / RNA Synthesis
  1. phosphoric acid halide