Uric Acid 尿酸

CAS 69-93-2 MFCD00005712

化学结构图

69-93-2
SMILES: O=c1[nH]c(=O)c2[nH]c(=O)[nH]c2[nH]1

化学属性

Mol. FormulaC5H4N4O3
Mol. Weight168.11
Density1.89
Melting Point>300°C
TSCAYes
Appearance crystalline
Boiling Point297.02 °C at 760 mmHg

别名和识别编码

Chemical NameUric acid
CAS Number69-93-2
Synonym Uric acid {LY} Uric acid {} {LY} Uric acid {} {} {LY} Uric acid {} {} {} {LY} Uric acid {} {} {} {} {PubChem} Uric Acid {} {} {} {} {} {PubChem} Urate, Sodium Acid {} {} {} {} {} {} {PubChem} Urate, Sodium {} {} {} {} {} {} {} {PubChem} Urate, Potassium {} {} {} {} {} {} {} {} {PubChem} Urate, Monosodium {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {PubChem} Urate, Ammonium Acid {} {} {} {} {} {} {} {} {} {} {PubChem} Urate Monohydrate, Sodium {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {PubChem} Urate Monohydrate, Monosodium {} {} {} {} {} {} {} {} {} {} {} {} {PubChem} Urate {} {} {} {} {} {} {} {} {} {} {} {} {} {PubChem} Trioxopurine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {PubChem} Sodium Urate Monohydrate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {PubChem} Sodium Urate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {PubCh
EC Number200-720-7
Beilstein Registry Number156158
MDL NumberMFCD00005712
PubChem Substance ID1175
Merck Number9875
Reaxys-RN156158
Chemical Name Translation尿酸
LabNetwork Molecule IDLN00194809
InChIInChI=1S/C5H4N4O3/c10-3-1-2(7-4(11)6-1)8-5(12)9-3/h(H4,6,7,8,9,10,11,12)
Canonical SMILESO=C(N1)NC2=C(NC(N2)=O)C1=O
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分类

  • {SNA} Core Bioreagents, Metabolic Pathways, Metabolites and Cofactors on the Metabolic Pathways Chart, Metabolomics, Nucleosides and Nucleotides, Nucleotide, Research Essentials
  • {uni_hamburg} no charge; nitrogen heterocycle; large ring; fused rings; 5ring; 6ring; 9ring; urea; amide; lactame; 1fragment
  • Heterocycles
  • {SNA} Biochemicals and Reagents, Core Bioreagents, Nucleosides, Nucleosides and Nucleotides, Nucleosides, Nucleotides, Oli
  • {SNA} Core Bioreagents, Metabolic Pathways, Metabolites and Cofactors on the Metabolic Pathways Chart, Nucleosides and Nucleotides, Nucleotide, Research Essentials, 代谢组学, 细胞生物学
  • Pharmaceuticals
  • {SNA} Building Blocks, Chemical Synthesis, Heterocyclic Building Blocks, Puri

产品应用

  • 主要用作合成辅酶ATP（三磷酸腺苷）的原料及检验钨酸盐。

相关文献及参考

  • [2]. Yasutake Y, et al. Uric acid ameliorates indomethacin-induced enteropathy in mice through its antioxidant activity. J Gastroenterol Hepatol. 2017 Nov;32(11):1839-1845.
  • Beilstein:26,513
  • Heinig, M. et al.: Cle. Clin. J. Med., 73, 1059 (2006); Glantzounis, G.K. et al.: Curr. Pharmac. Des., 11, 4145 (2005); Dehghan, A. et al.: Diab. Care, 31, 361 (2008); Nakagawa, T. et al.: Am. J. Phy
  • Short: II/27B
  • Short: III/39
  • [1]. Wang Q, et al. Recent Progress on Uric Acid Detection: A Review. Crit Rev Anal Chem. 2020;50(4):359-375.
  • [1]. Wang Q, et al. Recent Progress on Uric Acid Detection: A Review. Crit Rev Anal Chem. 2020;50(4):359-375.
  • [2]. Yasutake Y, et al. Uric acid ameliorates indomethacin-induced enteropathy in mice through its antioxidant activity. J Gastroenterol Hepatol. 2017 Nov;32(11):1839-1845.

安全信息

Signal word Warning
GHS Symbol
WGK Germany3
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R33 Danger of cumulative effects 有累积作用的危险
Precautionary statements
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RTECSYU7050080
Storage condition 2-8°C {LY} 2-8°C Store at RT. {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 10 mmol/L
REFERENCE :
   CYTBAI Cytobios. (Faculty Press, 88 Regent St., Cambridge, UK)  V.1- 1969- 
   Volume(issue)/page/year: 4,87,1971

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 5040 mg/kg
SEX/DURATION            : male 4 week(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
   TOIZAG Toho Igakkai Zasshi.  Journal of Medical Society of Toho University.
   (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143,
   Japan)  V.1-    1954-  Volume(issue)/page/year: 32,36,1985

Hazard statements

其他信息

  • 下游产品:咖啡因
  • 用途一:用作分析试剂，也用于有机合成
  • 尿酸价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 LA1334601 尿酸 25g 340元 2011/08/23 65012484 尿酸 25g 230元 2011/04/16 U0018 尿酸 Uric Acid 25G 324元
  • 用途二:主要用作合成辅酶ATP（三磷酸腺苷）的原料及检验钨酸盐。
  • 微溶于水，溶于热的浓硫酸和氢氧化钠碱溶液，溶于甘油、醋酸钠和磷酸钠，不溶于醇和醚。
  • Alfa Aesar:尿酸,99% Uric acid, 99%(69-93-2)
  • MOL 文件:69-93-2.mol
  • Sigma Aldrich:69-93-2(sigmaaldrich)
  • Acros Organics:尿酸 Uric acid, 99+%(69-93-2)
  • TCI Shanghai:尿酸 Uric Acid,>;98.0%(T)(69-93-2)

系列性分类

  1. Research Essentials 基础科研
  2. Core Bioreagents - Research Essentials
  3. Nucleosides and Nucleotides - Core Bioreagents
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Nucleosides, Nucleotides, Oligonucleotides - Biochemicals and Reagents
  4. Nucleoside Analogs - Nucleosides, Nucleotides, Oligonucleotides
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Nucleosides, Nucleotides, Oligonucleotides - Biochemicals and Reagents
  4. Nucleosides - Nucleosides, Nucleotides, Oligonucleotides
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Nucleosides, Nucleotides, Oligonucleotides - Biochemicals and Reagents
  4. Nucleotide Analogs - Nucleosides, Nucleotides, Oligonucleotides
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Nucleosides, Nucleotides, Oligonucleotides - Biochemicals and Reagents
  4. Nucleotides - Nucleosides, Nucleotides, Oligonucleotides
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Purines 嘌呤
  1. Life Science 生命科学
  2. Metabolomics 代谢组学
  3. Metabolic Pathways - Metabolomics
  4. Metabolites and Cofactors on the Metabolic Pathways Chart - Metabolic Pathways
  5. Nucleotide - Metabolites and Cofactors on the Metabolic Pathways Chart
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Nucleic Acid Electrophoresis
  4. Nucleic Acid Gel Stains
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Nucleosides, Nucleotides, Oligonucleotides
  4. Nucleoside Analogs
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Metabolomics
  4. Metabolic Pathways
  5. Metabolites and Cofactors on the Metabolic Pathways Chart
  6. Lipid
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Enzymes, Inhibitors, and Substrates
  4. Metabolomics
  5. Metabolic Pathways
  6. Metabolites and Cofactors on the Metabolic Pathways Chart
  7. Lipid
  1. Medical Research Areas
  2. Metabolism
  3. Reactive Oxygen Species  (活性氧)
  1. Medical Research Areas
  2. Metabolism
  3. Endogenous Metabolite  (内源性代谢物)

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