• 原料直供
• 试剂商城
• 直接询价

分类

• Aldehydes, Building Blocks, C8, Carbonyl Compounds, Chemical Synthesis, Organic Building Blocks
• {uni_hamburg} no charge; oxygen heterocycle; carbocycle; aromatic; alicycle; large ring; fused rings; 5ring; 6ring; 9ring; aldehyde; 1fragment
• {SNA} Aldehydes, Building Blocks, C8, Carbonyl Compounds, Chemical Synthesis, Organic Building Blocks

产品应用

• Piperonal is an impurity of Tadalafil (T004500). Tadalafil impurity A.

相关文献及参考

• Merck 14 ,7475
• Beil. 19 ,V,4,225
• Arctander , 1484 / FT-IR 1 (2), 119:A / FT-IR 2 (2), 2542:B / FT-NMR 1 (2), 956:B / Fenaroli , 680 / IR-Spectra (3), 919:A / IR-Spectra (2), 804:F / NMR-Reference 2 (2), 117:A / RegBook 84 (2), 1723:N / RegBook 1 (2), 1723:N / Sax 6 , 2241 / Structure Index 1 , 274:A:4 / Vapor Phase 3 , 1299:D
• Short: IV/1a Title: Densities of Liquid Systems: Nonaqueous Systems and Ternary Aqueous Systems Author: Lacmann, R.; Synowietz, C. Editor: Schäfer, Kl. Source: Landolt-Börnstein, New Series Volume: IV/1a Year: 1974 ISBN: 3-540-06269-6 ISBN: 978-3-540-06269-1 Internet Resource: DOI:10.1007/b20003 RefComment: X, 716 pages. Hardcover Abstract: Volume IV/1 contains information on the densities of liquid systems. It may be considered as a supplement to volume II/1 of the 6th Edition, which contains only a few data on nonaqueous systems. Data are not listed for all systems but primarily for those of greater interest where data for a larger range of concentrations were available.
• Short: IV/20B Title: Vapor Pressure and Antoine Coefficients for Oxygen Containing Organic Compounds Author: Dykyj, J.; Svoboda, J.; Wilhoit, R.C.; Frenkel, M.; Hall, K.R. Editor: Hall, K.R. Source: Landolt-Börnstein, New Series Volume: IV/20B Year: 2000 Keyword: organic compounds; vapor pressure ISBN: 3-540-64968-9 ISBN: 978-3-540-64968-7 Internet Resource: DOI:10.1007/b71424 RefComment: VII, 320 pages.
• Short: EINECS Title: EINECS (European Inventory of Existing Commercial Chemical Substances) Source: Official Journal of the European Communities Volume: C 146 A (15.06.1990) Page: 1 Year: 1990 Internet Resource: http://ecb.jrc.ec.europa.eu/esis/index.php?PGM=ein Publish_Date: 1990/06/15

安全信息

GHS Symbol

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1500 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - muscle weakness
   Behavioral - ataxia
REFERENCE :
   RMSRA6 Revue Medicale de la Suisse Romande.  (Societe Medicale de La Suisse
   Romande, 2 rue Bellefontaine, 1003 Lausanne, Switzerland)  V.1-    1881-
   Volume(issue)/page/year: 16,449,1896

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >5 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientifi

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2700 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - excitement
   Behavioral - ataxia
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   6,378,1964

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 480 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - respiratory depression
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 43,370,1954

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Bird - chicken Embryo
DOSE/DURATION           : 2 mg
REFERENCE :
   CHYCDW Zhonghua Yufangyixue Zazhi.  Chinese Journal of Preventive Medicine.
   (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep.
   China)  Beginning history not known.  Volume(issue)/page/year: 20,254,1986

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 120 ug/L
REFERENCE :
   CHYCDW Zhonghua Yufangyixue Zazhi.  Chinese Journal of Preventive Medicine.
   (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep.
   China)  Beginning history not known.  Volume(issue)/page/year: 20,254,1986

其他信息

• 胡椒醛价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2010/06/21 131341000 胡椒醛 Piperonal 99% 100 GR 301元 2010/06/21 131345000 胡椒醛 Piperonal 99% 500 GR 1132元 2010/06/21 131340050 胡椒醛 Piperonal 99% 5 GR 222元
• 所属类别一:食品添加剂: 食用香料（增香剂）: 天然等同香料和人造香
• 下游产品:1-胡椒基哌嗪 --> 黄莲素 --> 亚胡椒基乙酰氯 --> 3,4-(亚甲二氧)肉桂酸 --> 6-硝基胡椒醛 --> 胡椒酸
• {Chemica
• 用途一:用于配制花香型和幻想型香精，也用于电镀
• 用途五:有机合成，制造香料，电镀光亮剂，农药增效剂。 广泛用于医药上，以及配制花香型和幻想型香精。
• 方法一:以邻苯二酚为原料合成 先在高压釜中加入6.42g(0.02mo1)溴化四丁铵、100mL二氯甲烷(1.56mo1)和200mL水，然后慢慢加入15g(0.1362mo1)邻苯二酚和15.9g(0.3975mo1)氢氧化钠。反应温度保持在70℃，压力最大不超过0.25MPa。反应完成后分出有机相，回收过量的二氯甲烷后蒸馏得到13.8g邻苯二酚亚甲醚，收率为83%。 将103g聚甲醛溶解于1L的浓盐酸中，随后加入535g
• {Chem
• 用途三:GB 2760—96规定为暂时允许使用的食用香料。主要用以配制香草、樱桃、桃、梅、草莓、可乐、酒和烟草等型香精。
• {Ch
• 用途四:该品具有类似香水草花（俗称葵花，洋茉莉）的香气，主要用于葵花、百合、紫罗兰等多种花香型和幻想型化妆品香精中，在食品、烟草中变有应用。天芥菜精还和合成法黄连素的中间体。也用作农药增效剂和电镀添加剂。
• 含量分析:按醛测定法(OT-6)测定。所取试样量为1.5g。计算中的当量因子(e)取75.06。 或按气相色谱法(GT-10-4)中用非极性柱方法分析。
• Sigma Aldrich:120-57-0(sigmaaldrich)
• Alfa Aesa
• 上游原料:三氯甲烷 --> 多聚甲醛 --> 乌洛托品 --> 重铬酸钠 --> 重铬酸钾 --> 邻苯二酚 --> 浓盐酸 --> 四丁基溴化铵 --> 对氨基苯磺酸 --> 1,2-亚甲二氧基苯 --> 氢氧化钾-乙醇 --> 黄樟素 --> 异黄樟素 --> 黄樟油 --> 胡椒基氯化物
• 蒸气压:1 mm Hg ( 87 °C)
• 参考质量标准二:QB 1788—1993 色状 白色晶体 香气 似香水草花香气 醇中溶解度 1g溶于4mL 95%乙醇中 含量/% ≥99.0 凝固点/℃ ≥35
• {C
• 食品添加剂最大允许使用量最大允许残留量标准:添加剂中文名称 允许使用该种添加剂的食品中文名称 添加剂功能 最大允许使用量（g/kg） 最大允许残留量（g/kg） 洋茉莉醛 食品 食品用香料 用于配制香精的各香料成分不得超过在GB 2760中的最大允许使用量和最大允许残留量
• 用途二:洋茉莉醛是我国《食品添加剂使用卫生标准》规定暂时允许使用的食品香料，主要用于配制香草、桃、梅、草莓、樱桃等食用香精，用于可乐、酒和烟草等。在口香糖中使用量为36mg/kg；烘烤食品中18mg/kg；糖果中7.4mg/kg；冷饮中7.0mg/kg；软饮料中6.0mg/kg；布丁类中5.8mg/kg。
• 所属类别二:食品添加剂: 食品香料
• 参考质量标准一:QB 1788—93(强制性标准)@FCC，1996 含醛量 ≥99.0% ≥99.0% 凝固点 ≥35℃ ≥35℃醇中溶解度(OT-43) 1g溶于4mL 95%乙醇中 1g溶于4mL 70%乙醇 色状 白色晶体 - 香气 似香水草花香气 - 重金属(GT-16-2) ≤0.04% - 铅(GT-8) ≤10 mg/kg
• 图谱信息:胡椒醛(120-57-0)质谱(MS) 胡椒醛(120-57-0)红外图谱(IR1) 胡椒醛(120-57-0)红外图谱(IR2)