CAS 58-96-8 MFCD00006526-Uridine 尿嘧啶核苷 -LabNovo

Uridine 尿嘧啶核苷

CAS 58-96-8 MFCD00006526

化学结构图

SMILES: O=c1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]1

化学属性

Mol. Formula	C9H12N2O6
Mol. Weight	244.20
Density	1.1
Melting Point	163-167°C
TSCA	Yes
Appearance	powder 白色针状结晶或粉末。无气味，味稍甜而微辛。mp165℃。比旋度+4°(20℃，C=2，水中)。系核苷类的一种。能溶于水，微溶于稀醇，不溶于无水乙醇。
Solubility	H2O: 50 mg/mL
Refractive index	9 ° (C=2, H2O)
Boiling Point	387.12 °C at 760 mmHg

别名和识别编码

Chemical Name	Uridine
CAS Number	58-96-8
Alfabeta Name	URIDINE
MDL Number	MFCD00006526
Synonym	Uridine {LY} Uridine {} {LY} Uridine {} {} {LY} Uridine {} {} {} {LY} Uridine {} {} {} {} {LY} Uridine {} {} {} {} {} {LY} Uridine {} {} {} {} {} {} { {} {} {} {} {} {} {LY} Uridine {} {} {} {} {} {} {} {LY} Uridine {} {} {} {} {} {} {} {} {LY} Uridine {} {} {} {} {} {} {} {} {} {LY} Uridine {} {} {} {} {} {} {} {} {} {} {LY} Uridine {} {} {} {} {} {} {} {} {} {} {} {LY} Uridine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {LY} Uridine {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Uridine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Uridine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Uridine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Uridine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Uridine {} {} {} {} {} {} {} {} {} {} {}
EC Number	200-407-5
Beilstein Registry Number	754902
PubChem Substance ID	6029
Merck Number	9877
Reaxys-RN	754904
Chemical Name Translation	尿嘧啶核苷
LabNetwork Molecule ID	LN00008482
InChI	InChI=1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1
Canonical SMILES	O[C@H]1[C@@H](O)[C@H](N2C(NC(C=C2)=O)=O)O[C@@H]1CO

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产品应用

尿苷是一种药物，如抗巨型红血球贫血，治疗肝；脑血管；心血管等疾病，也是制造氟尿嘧啶(S-FC)；脱氧核苷；碘苷(IDUR)；溴苷(BUDR)；氟苷(FUDR)等药物的主要原料。

安全信息

Warnings IRRITANT

Signal word Warning

GHS Symbol

WGK Germany3

Safety Statements

S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；

Risk Statements

R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

Precautionary statements

P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。

Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

RTECSYR1450000

Storage condition Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4335 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 207,504,1978

TYPE OF TEST            : Micronucleus test
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 740 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 301,45,1993

TYPE OF TEST            : DNA damage
TEST SYSTEM             : Mammal - species unspecified Lymphocyte
DOSE/DURATION           : 100 mmol/L
REFERENCE :
   PNASA6 Proceedings of the National Academy of Sciences of the United States
   of America.  (National Academy of Sciences, Printing & Pub. Office, 2101
   Constitution Ave., Washington, DC 20418) V.1-    1915-
   Volume(issue)/page/year: 48,686,1962

其他信息

用途三:尿苷是一种药物，如抗巨型红血球贫血，治疗肝、脑血管、心血管等疾病，也是制造氟尿嘧啶(S-FC)、脱氧核苷、碘苷(IDUR)、溴苷(BUDR)、氟苷(FUDR)等药物的主要原料。
尿苷价格(试剂级):更新日期产品编号产品名称包装价格 2011/08/23 65012581 尿苷;尿嘧啶核苷;二氢嘧啶核苷;尿核苷;1-β-D-呋喃核糖基尿嘧啶;NFDB2NFDB3-1-β-D-呋喃核苷 5g 295元 2011/08/23 SU375001 尿苷;尿嘧啶核苷;二氢嘧啶核苷;尿核苷;1-β-D-呋喃核糖基尿嘧啶;NFDB2NFDB3-1-β-D-呋喃核苷 1g 330元 2011/04/16 U0020 尿嘧啶核苷 Uridine 25G 925元
比旋光度:8.4 ° (c=2,water)
Alfa Aesar:尿(嘧啶核)苷,99% Uridine, 99%(58-96-8)
用途一:用于制造氟尿嘧啶脱氧核苷、碘苷等抗肿瘤药物
MOL 文件:58-96-8.mol
无气味。味稍甜而微辛。能溶于水，微溶于稀醇，不溶于无水乙醇。构成动物细胞核酸的有关成分。
用途二:本品可用于巨型红血球贫血，也可与其他核苷、碱基合用于治疗肝、脑血管及心血管等疾患。
Acros Organics:脲嘧啶核苷/尿苷 Uridine,99%(58-96-8)
图谱信息:尿苷(58-96-8)Raman光谱尿苷(58-96-8)核磁图( 13 CNMR) 尿苷(58-96-8)核磁图( 1 HNMR) 尿苷(58-96-8)红外图谱(IR1) 尿苷(58-96-8)红外图谱(IR2)
检测方法:HPLC
用途四:尿苷是一种药物，如抗巨型红血球贫血，治疗肝；脑血管；心血管等疾病，也是制造氟尿嘧啶(S-FC)；脱氧核苷；碘苷(IDUR)；溴苷(BUDR)；氟苷(FUDR)等药物的主要原料。
TCI Shanghai:尿(嘧啶核)苷 Uridine,>;98.0%(T)(58-96-8)
F:10
MSDS 信息:Uridine(58-96-8).msds
Hazard Note:Keep Cold
下游产品:阿糖腺苷 --> 5'-核糖核苷酸钙
Sigma Aldrich:58-96-8(sigmaaldrich)