Isobutylamine 异丁胺

CAS 78-81-9 MFCD00008146

化学结构图

78-81-9
SMILES: CC(C)CN

化学属性

Mol. FormulaC4 H11 N
Mol. Weight73.14
Density0.736
Refractive index1.3950 to 1.3980
Boiling Point66°C
Melting Point-85
Flash Point-9°C(lit.)
TSCAYes
Solubility可溶
Danger-Level甲类

别名和识别编码

Chemical NameIsobutylamine
Synonym (2-methylpropyl)amine 1-Amino-2-methylpropane 1-Amino-2-methylpropane; 2-Methyl-1-propanamine; 2-Methylpropanamine 1-Aminoisobutane 1-amino-2-methyl-propane 2-METHYL-1-PROPANAMINE 2-METHYLPROPYLAMINE 2-Methyl-1-aminopropane 2-Methylpropylamine {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {
MDL NumberMFCD00008146
CAS Number78-81-9
EC Number201-145-4
Beilstein Registry Number4,163
PubChem Substance ID87571496
Merck Number5132
Reaxys-RN385626
Chemical Name Translation异丁胺
Wiswesser Line NotationZ1Y1&1
LabNetwork Molecule IDLN00222730
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分类

  • {SNA} Amines, Building Blocks, C2 to C5,
  • {SNA} Amines, Building Blocks, C2 to C5, Cell Biology, Chemical Synthesis, Nitrogen Compounds, Nutrition Research, Organic Building Blocks, Phytochemicals by Plant (Food/Spice/Herb), Sambucus nigra (Elderberry)
  • {uni_hamburg} no charge; 1fragment
  • {SNA} Alphabetical Listings, Flavors and Fragrances, I-L
  • {SNA} Amines, Building Blocks, C2 to C5, Chemical Synthesis, Nitrogen Compounds, Nutrition Research, Organic Building Blocks, Phytochemicals by Plant (Food/Spice/Herb), Sambucus nigra (Elderberry), 细胞生物学
  • {SNA} Amines,

产品应用

  • 用作生产杀虫剂、缓蚀剂和橡胶加工化学品的有机合成中间体。易然、腐蚀性，应常温、干燥、密闭保存。

相关文献及参考

  • Beilstein:4,163
  • Short: II/27B
  • Short: III/35B

安全信息

Signal word
GHS Symbol
WGK Germany1
Safety Statements
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
  • S20 When using do not eat or drink 使用时，不得进食，饮水；
  • S33 Take precautionary measures against static discharges 对静电采取预防措施；
  • S43 In case of fire use ... (indicate in the space the precise type of fire-fighting equipment. If water increases the risk add -?Never use water) 着火时使用（指明具体的消防器材种类，如果用水增加危险，注明“禁止用水”
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
  • S7 Keep container tightly closed 保存在严格密闭容器中；
Risk Statements
  • R35 Causes severe burns 会导致严重灼伤
  • R22 Harmful if swallowed 吞咽有害
  • R11 Highly flammable 非常易燃
  • R34 Causes burns 会导致灼伤
Precautionary statements
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P303+P361+P353+P310+P363
  • P301+P310
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338+P310
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P301+P330+P331+P310
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
Hazard statements
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H301 Toxic if swallowed 吞食有毒
Personal Protective Equipment Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECSNP9900000
Packing GroupII
UN Number 1214
Hazard Codes F,C
Storage condition +4°C 4℃ 密封阴凉保存。
Hazard Class3/8
Warnings 危化品目录(2015) 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 224 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
   Behavioral - antipsychotic
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   63,150,1982

Restrict 危险品

其他信息

  • Alfa Aesar:异丁胺,99% Isobutylamine, 99%(78-81-9)
  • 检测方法:GC
  • FEMA:4239
  • 上游原料:异丁醇 --> 异丁醛 --> 对甲苯磺酰胺 --> 溴代异丁烷
  • Sigma Aldrich:78-81-9(sigmaaldrich)
  • 灭火剂:干粉、干砂、二氧化碳、泡沫
  • 用途二:用于有机合成和杀虫剂的合成
  • 用途一:溶于水和大多数的有机溶剂。用作矿物浮选剂、汽油抗震剂和磺基苯甲酸十三烷基酯的中和剂。
  • 有氨臭。有强碱性。能与水、乙醇和乙醚混溶。易燃。有腐蚀性。
  • 类别:易燃液体
  • MSDS 信息:异丁胺(78-81-9).msds
  • 异丁胺价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 K5848001 异丁胺;1-氨基异丁烷;2-甲基丙胺 250ml 478元 2011/04/16 I0095 异丁胺 Isobutylamine 500ML 400元 2011/04/16 I0095 异丁胺 Isobutylamine 25ML 109元
  • 方法一:1.由异丁醇与氨作用催化脱水制得醇经氨解反应后可得伯、仲、叔胺的混合产物，三种胺生成的比例与原料、催化剂及反应条件有关。通过调节醇和氨的比例及反应条件，可以得到的所期望的产品比例。2.由异丁醛和氨经催化加氢制得。3.以溴代异丁烷与对甲苯磺酰胺为原料，经缩合、水解而得。先将对甲苯磺酰胺、溴代异丁烷、乙醇碱液一起回流4h，回收乙醇至出现结晶，再用盐酸中和，则析出大量淡黄色结晶，过滤，水洗得缩合物。将缩合物、硫酸和水混合加热回流10h后，改为蒸馏装置，加40%液碱调至碱性，随后减压蒸出粗胺，再粗馏收集66.8-68.8℃馏分即为成品。
  • MOL 文件:78-81-9.mol
  • 用途三:用于生产杀虫剂、缓蚀剂和橡胶助剂
  • 下游产品:异丁腈
  • 急性毒性:口服- 大鼠 LD50: 224 毫克/ 公斤
  • TCI Shanghai:异丁胺 Isobutylamine,>;98.0%(GC)(78-81-9)
  • 可燃性危险特性:遇明火、高温、氧化剂易燃; 燃烧产生有毒氮氧化物烟雾
  • 毒性分级:高毒
  • 图谱信息:异丁胺(78-81-9)红外图谱(IR1) 异丁胺(78-81-9)质谱(MS) 异丁胺(78-81-9)核磁图( 13 CNMR) 异丁胺(78-81-9)Raman光谱 异丁胺(78-81-9)红外图谱(IR2)
  • 职业标准:TWA 15 毫克/ 立方米; STEL 75 毫克/ 立方米
  • 用途四:有机合成原料，用于合成杀虫剂，也可用作试剂。还用作矿物浮选剂，汽油抗震剂、聚合催化剂和稳定剂等。
  • 储运特性:库房通风低温干燥; 与氧化剂、酸类分开存放
  • F:10-23
  • 用途五:用作生产杀虫剂、缓蚀剂和橡胶加工化学品的有机合成中间体。易然、腐蚀性，应常温、干燥、密闭保存。
  • 外观性质:无色液体，有氨的气味。

系列性分类

  1. C2 to C5 - Amines
  1. C10 - Amines