1-Bromo-2-fluorobenzene 邻氟溴苯

CAS 1072-85-1 MFCD00000282

化学结构图

1072-85-1
SMILES: Fc1ccccc1Br

化学属性

Mol. FormulaC6H4BrF
Mol. Weight175.00
Boiling Point78-82 °C at 50 mmHg
TSCAT
Density1.601
Refractive index1.5330 to 1.5350
Flash Point50.2°C
Melting Point-8 °C
Solubility不溶
Appearance 淡黄色液体。沸点155℃-157℃,闪点43℃,折光率1.5340,比重1.601。

别名和识别编码

Chemical Name1-Bromo-2-fluorobenzene
CAS Number1072-85-1
Alfabeta NameBROMOFLUOROBENZENE 12---
MDL NumberMFCD00000282
Synonym 1-Bromo-2-fluorobenzene {LY} 1-Bromo-2-fluorobenzene {} {LY} 1-Bromo-2-fluorobenzene {} {} {LY} 1-Bromo-2-fluorobenzene {} {} {} {LY} 1-Bromo-2-fluorobenzene {} {} {} {} {LY} 1-Bromo-2-fluorobenzene {} {} {} {} {} {LY} 1-Bromo-2-fluorobenzene {} {} {} {} {} {} {LY} 1-Bromo-2-fluorobenzene {} {} {} {} {} {} {} {LY} 1-Bromo-2-fluorobenzene {} {} {} {} {} {} {} {} {LY} 1-Bromo-2-fluorobenzene {} {} {} {} {} {} {} {} {} {LY} 1-Bromo-2-fluorobenzene {} {} {} {} {} {} {} {} {} {} {LY} 1-Bromo-2-fluorobenzene {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Bromo-2-fluorobenzene {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Bromo-2-fluorobenzene {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Bromo-2-fluorobenzene {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Bromo-2-fluorobenzene {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Bromo-2-fluorobenzene {} {} {} {} {} {} {} {} {} {} {} {} {}
EC Number214-018-3
Beilstein Registry Number1071819
PubChem Substance ID61259
Reaxys-RN1071819
Chemical Name Translation邻氟溴苯
InChIKeyIPWBFGUBXWMIPR-UHFFFAOYSA-N
Wiswesser Line NotationFR BE
LabNetwork Molecule IDLN00115991
InChIInChI=1S/C6H4BrF/c7-5-3-1-2-4-6(5)8/h1-4H
Canonical SMILESFC1=CC=CC=C1Br
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分类

  • {SNA} Aryl, Aryl Fluorinated Building Blocks, Building Blocks, C6, Chemical Synthesis, Fluorinated Building Blocks, Halogenated Hydrocarbons, Organic Building Blocks, Organic Fluorinated Building Blocks, Other Fluorinated Organic Building Blocks
  • {uni_hamburg} no charge; carbocycle; aromatic; 6RingOnly; 6ring; 1fragment

产品应用

  • 医药、农药、液晶材料中间体。

相关文献及参考

  • On treatment with Mg: J. Org. Chem., 49, 4518 (1984), or n-BuLi: Tetrahedron, 48, 4379 (1992), benzyne is generated, which undergoes [4+2] cycloadditions with furans or pyrroles.
  • Short: III/35D2
  • Short: III/38B
  • Whereas n-BuLi effects bromine-metal exchange, lithiation with LDA at -75o results in deprotonation ortho to F; subsequent reaction with electrophiles provides access to mixed dihalo derivatives such as 3-bromo-2-fluorobenzoic acid: Tetrahedron Lett., 36, 881 (1995). Improved yields are obtained by the use of lithium 2,2,6,6-tetramethylpiperidide (LTMP) as base: Tetrahedron Lett., 37, 6551 (1996).
  • Beilstein: 5,IV,678

安全信息

Warnings IRRITANT, FLAMMABLE
Signal word Warning
GHS Symbol
WGK Germany3
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
Risk Statements
  • R10 Flammable 易燃
  • R22 Harmful if swallowed 吞咽有害
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P312+P330
  • P303+P361+P353
  • P305+P351+P338
  • P332+P313
  • P337+P313
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H226 Flammable liquid and vapour 易燃液体和蒸气
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECSDA1050000
Packing GroupIII
UN Number 1993
Hazard Codes 3 Xn
Hazard Class3
Storage condition Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}

其他信息

  • MSDS 信息:1-Bromo-2-fluorobenzene(1072-85-1).msds
  • TCI Shanghai:1-氟-2-溴苯 2-Bromofluorobenzene,>;99.0%(GC)(1072-85-1)
  • MOL 文件:1072-85-1.mol
  • 用途一:用作医药、农药中间体
  • TSCA:T
  • 下游产品:1,4-环氧-1,4-二氢萘
  • Alfa Aesar:1-溴-2-氟苯,98% 1-Bromo-2-fluorobenzene, 99%(1072-85-1)
  • 图谱信息:邻溴氟苯(1072-85-1)质谱(MS) 邻溴氟苯(1072-85-1)红外图谱(IR1) 邻溴氟苯(1072-85-1)核磁图( 13 CNMR) 邻溴氟苯(1072-85-1)核磁图( 1 HNMR)
  • 海关编码:29036990
  • 邻溴氟苯价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 xw010066 邻氟溴苯 100g 880元 2011/04/16 B0883 2-溴氟苯 2-Bromofluorobenzene 500G 4900元 2011/04/16 B0883 2-溴氟苯 2-Bromofluorobenzene 25G 460元
  • Acros Organics:2-Bromofluorobenzene, 99%(1072-85-1)
  • Hazard Note:Flammable/Irritant
  • Sigma Aldrich:1072-85-1(sigmaaldrich)
  • 用途二:医药、农药、液晶材料中间体。

系列性分类